日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Alanine Scanning Mutagenesis of the MEDI4893 (Suvratoxumab) Epitope Reduces Alpha Toxin Lytic Activity In Vitro and Staphylococcus aureus Fitness in Infection Models

MEDI4893(Suvratoxumab)表位的丙氨酸扫描诱变可降低体外 Alpha 毒素溶解活性和感染模型中的金黄色葡萄球菌适应性

C Tkaczyk, E Semenova, Y Y Shi, K Rosenthal, V Oganesyan, P Warrener, C K Stover, B R Sellman

Multimechanistic Monoclonal Antibodies (MAbs) Targeting Staphylococcus aureus Alpha-Toxin and Clumping Factor A: Activity and Efficacy Comparisons of a MAb Combination and an Engineered Bispecific Antibody Approach

针对金黄色葡萄球菌 Alpha 毒素和凝集因子 A 的多机制单克隆抗体 (MAb):MAb 组合和工程化双特异性抗体方法的活性和功效比较

C Tkaczyk, S Kasturirangan, A Minola, O Jones-Nelson, V Gunter, Y Y Shi, K Rosenthal, V Aleti, E Semenova, P Warrener, D Tabor, C K Stover, D Corti, G Rainey, B R Sellman

Assessment of an anti-alpha-toxin monoclonal antibody for prevention and treatment of Staphylococcus aureus-induced pneumonia

抗α毒素单克隆抗体预防和治疗金黄色葡萄球菌引起的肺炎的评估

L Hua, J J Hilliard, Y Shi, C Tkaczyk, L I Cheng, X Yu, V Datta, S Ren, H Feng, R Zinsou, A Keller, T O'Day, Q Du, L Cheng, M Damschroder, G Robbie, J Suzich, C K Stover, B R Sellman

Identification of anti-alpha toxin monoclonal antibodies that reduce the severity of Staphylococcus aureus dermonecrosis and exhibit a correlation between affinity and potency

鉴定可降低金黄色葡萄球菌皮肤坏死严重程度且具有亲和力和效力相关性的抗α毒素单克隆抗体

C Tkaczyk, L Hua, R Varkey, Y Shi, L Dettinger, R Woods, A Barnes, R S MacGill, S Wilson, P Chowdhury, C K Stover, B R Sellman

Short-term hormone treatment modulates emotion response circuitry in postmenopausal women

短期激素治疗可调节绝经后女性的情绪反应回路

Love, Tiffany; Smith, Yolanda R; Persad, Carol C; Tkaczyk, Anne; Zubieta, Jon-Kar

Impact of combined estradiol and norethindrone therapy on visuospatial working memory assessed by functional magnetic resonance imaging

雌二醇和炔诺酮联合治疗对视觉空间工作记忆的影响(通过功能磁共振成像评估)

Smith, Yolanda R; Love, Tiffany; Persad, Carol C; Tkaczyk, Anne; Nichols, Thomas E; Zubieta, Jon-Kar