Immuno-PET Monitoring of CD8(+) T Cell Infiltration Post ICOS Agonist Antibody Treatment Alone and in Combination with PD-1 Blocking Antibody Using a (89)Zr Anti-CD8(+) Mouse Minibody in EMT6 Syngeneic Tumor Mouse
在EMT6同源肿瘤小鼠模型中，使用(89)Zr抗CD8(+)小鼠微型抗体，通过免疫PET监测ICOS激动剂抗体单独治疗以及与PD-1阻断抗体联合治疗后CD8(+) T细胞的浸润情况。
期刊:Molecular Imaging and Biology
影响因子:2.5
doi:10.1007/s11307-022-01781-7
Alsaid, Hasan; Cheng, Shih-Hsun; Bi, Meixia; Xie, Fang; Rambo, Mary; Skedzielewski, Tinamarie; Hoang, Bao; Mohanan, Sunish; Comroe, Debra; Gehman, Andrew; Hsu, Chih-Yang; Farhangi, Kamyar; Tran, Hoang; Sherina, Valeriia; Doan, Minh; Groseclose, M Reid; Hopson, Christopher B; Brett, Sara; Wilson, Ian A; Nicholls, Andrew; Ballas, Marc; Waight, Jeremy D; Jucker, Beat M
肿瘤
T细胞
肿瘤免疫
ICOS
CD8
T细胞
细胞生物学
Mouse
PD-1
免疫/内分泌
