Synthetic ZFTA fusions pinpoint disordered protein domain acquisition as a mechanism of brain tumorigenesis.
合成的 ZFTA 融合蛋白揭示了无序蛋白质结构域的获得是脑肿瘤发生的机制。
期刊:Nature Cell Biology
影响因子:19.1
doi:10.1038/s41556-025-01745-3
Arabzade A, Shirnekhi H K, Varadharajan S, Ippagunta S M, Phillips A H, Laboe N, Baggett D W, Wahiduzzaman, Jo M, Zheng T, Pathak R, Gee D, Bhimsaria D, Wu H, Gao X, Liu J, Emanus E, Bland A, Kardian A, Hancock A, Holcomb B, Wright T, Bugbee T, Sun H, Zhai M, Caesar E, Park M, Tripathi S, Shirinifard A, Lowe K, Khalighifar A, Petersen R A, King S, Stabley D, Pitre A, Campbell G E, Park C-G, Freyaldenhoven W T, Chandra B, Xia Y, Bonten E, Achari A, Kandikonda S, Carisey A, Pounds S B, Xu J, Ellison D W, Deneen B, Bertrand K C, Kriwacki R W, Mack S C
