日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Systematic elucidation and pharmacologic targeting on non-oncogene dependencies in imatinib-resistant gastrointestinal stromal tumor

系统阐明和药物靶向治疗伊马替尼耐药性胃肠道间质瘤中的非癌基因依赖性

Mundi, Prabhjot S; Grunn, Adina; Kojadinovic, Arsenije; Karan, Charles; Realubit, Ronald; Caescu, Cristina I; Hibshoosh, Hanina; Aburi, Mahalaxmi; Alvarez, Mariano J; Ingham, Matthew; Evans, Denisse; Rothschild, Sara; Schwartz, Gary K; Califano, Andrea

A Transcriptome-Based Precision Oncology Platform for Patient-Therapy Alignment in a Diverse Set of Treatment-Resistant Malignancies.

基于转录组的精准肿瘤学平台,用于针对多种难治性恶性肿瘤的患者-治疗方案匹配

Mundi Prabhjot S, Dela Cruz Filemon S, Grunn Adina, Diolaiti Daniel, Mauguen Audrey, Rainey Allison R, Guillan Kristina, Siddiquee Armaan, You Daoqi, Realubit Ronald, Karan Charles, Ortiz Michael V, Douglass Eugene F, Accordino Melissa, Mistretta Suzanne, Brogan Frances, Bruce Jeffrey N, Caescu Cristina I, Carvajal Richard D, Crew Katherine D, Decastro Guarionex, Heaney Mark, Henick Brian S, Hershman Dawn L, Hou June Y, Iwamoto Fabio M, Jurcic Joseph G, Kiran Ravi P, Kluger Michael D, Kreisl Teri, Lamanna Nicole, Lassman Andrew B, Lim Emerson A, Manji Gulam A, McKhann Guy M, McKiernan James M, Neugut Alfred I, Olive Kenneth P, Rosenblat Todd, Schwartz Gary K, Shu Catherine A, Sisti Michael B, Tergas Ana, Vattakalam Reena M, Welch Mary, Wenske Sven, Wright Jason D, Canoll Peter, Hibshoosh Hanina, Kalinsky Kevin, Aburi Mahalaxmi, Sims Peter A, Alvarez Mariano J, Kung Andrew L, Califano Andrea

Inhibition of HIPK2 Alleviates Thoracic Aortic Disease in Mice With Progressively Severe Marfan Syndrome

抑制 HIPK2 可减轻进展性严重马凡氏综合征小鼠的胸主动脉疾病

Cristina I Caescu #, Jens Hansen #, Brittany Crockett #, Wenzhen Xiao, Pauline Arnaud, Bart Spronck, Alan Weinberg, Takeshi Hashimoto, Sae-Il Murtada, Roshan Borkar, James M Gallo, Guillaume Jondeau, Catherine Boileau, Jay D Humphrey, John Cijiang He, Ravi Iyengar, Francesco Ramirez

Systems pharmacology-based integration of human and mouse data for drug repurposing to treat thoracic aneurysms

基于系统药理学的人类和小鼠数据整合,用于药物再利用治疗胸动脉瘤

Jens Hansen, Josephine Galatioto, Cristina I Caescu, Pauline Arnaud, Rhodora C Calizo, Bart Spronck, Sae-Il Murtada, Roshan Borkar, Alan Weinberg, Evren U Azeloglu, Maria Bintanel-Morcillo, James M Gallo, Jay D Humphrey, Guillaume Jondeau, Catherine Boileau, Francesco Ramirez, Ravi Iyengar

Cell Type-Specific Contributions of the Angiotensin II Type 1a Receptor to Aorta Homeostasis and Aneurysmal Disease-Brief Report

血管紧张素II 1a型受体对主动脉稳态和动脉瘤疾病的细胞类型特异性贡献——简报

Galatioto, Josephine; Caescu, Cristina I; Hansen, Jens; Cook, Jason R; Miramontes, Irving; Iyengar, Ravi; Ramirez, Francesco

Marfan syndrome; A connective tissue disease at the crossroads of mechanotransduction, TGFβ signaling and cell stemness

马凡氏综合征;一种结缔组织疾病,涉及机械转导、TGFβ信号传导和细胞干性等多个方面。

Ramirez, Francesco; Caescu, Cristina; Wondimu, Elisabeth; Galatioto, Josephine

Colony stimulating factor-1 receptor signaling networks inhibit mouse macrophage inflammatory responses by induction of microRNA-21

集落刺激因子-1受体信号网络通过诱导microRNA-21抑制小鼠巨噬细胞炎症反应

Cristina I Caescu, Xingyi Guo, Lydia Tesfa, Tushar D Bhagat, Amit Verma, Deyou Zheng, E Richard Stanley

Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10

金属蛋白酶TACE和ADAM10底物识别的活性位点决定因素

Caescu, Cristina I; Jeschke, Grace R; Turk, Benjamin E

Bifidobacterium longum requires a fructokinase (Frk; ATP:D-fructose 6-phosphotransferase, EC 2.7.1.4) for fructose catabolism

长双歧杆菌需要果糖激酶(Frk;ATP:D-果糖 6-磷酸转移酶,EC 2.7.1.4)来进行果糖分解代谢

Cristina I Caescu, Olivier Vidal, Frédéric Krzewinski, Vlad Artenie, Stéphane Bouquelet