Optimization of 3-Pyrimidin-4-yl-oxazolidin-2-ones as Allosteric and Mutant Specific Inhibitors of IDH1
优化 3-嘧啶-4-基-噁唑烷-2-酮类化合物作为 IDH1 的变构抑制剂和突变体特异性抑制剂
期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.6b00334
Levell, Julian R; Caferro, Thomas; Chenail, Gregg; Dix, Ina; Dooley, Julia; Firestone, Brant; Fortin, Pascal D; Giraldes, John; Gould, Ty; Growney, Joseph D; Jones, Michael D; Kulathila, Raviraj; Lin, Fallon; Liu, Gang; Mueller, Arne; van der Plas, Simon; Slocum, Kelly; Smith, Troy; Terranova, Remi; Touré, B Barry; Tyagi, Viraj; Wagner, Trixie; Xie, Xiaoling; Xu, Ming; Yang, Fan S; Zhou, Liping X; Pagliarini, Raymond; Cho, Young Shin