日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Metabolic reprogramming of the neovascular niche promotes regenerative angiogenesis in proliferative retinopathy.

新生血管微环境的代谢重编程促进增殖性视网膜病变中的再生血管生成

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-60061-4
Cagnone Gael, Pundir Sheetal, Betus Charlotte, Agnihotri Tapan, Ren Anli, -Kim Jin Sung, Harvey Noémie-Rose, Heckel Emilie, Chen Mei Xi, Situ Anu, Gaub Perrine, Kim Nicholas, Das Ashim, Leclerc Severine, Wünnemann Florian, Berillon Louis, Andelfinger Gregor, Crespo-Garcia Sergio, Dubrac Alexandre, Rezende Flavio A, Clish Clary B, Maranda Bruno, Rivera José Carlos, Smith Lois E H, Sapieha Przemyslaw, Joyal Jean-Sébastien
代谢
Angiogenesis
代谢重编程
血管生成
发表日期：2025
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Characterization of endothelin-converting enzyme 1 as a key enzyme in the multienzyme Aβ degradation pathway.

内皮素转化酶 1 的特性分析表明，它是多酶 Aβ 降解途径中的关键酶。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2507450122
Ulku Irem, Ansari Fatima El, Hancock Mark A, Zhou Hedi, Cagnone Gael, Joyal Jean-Sebastien, Fisher Teddy A J, Kennedy Timothy E, Liebsch Filip, Multhaup Gerhard
发表日期：2025
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Targeting angiopoietin like-2 positive senescent cells improves cognitive impairment in adult male but not female atherosclerotic LDLr(-/-);hApoB(100)(+/+) mice

靶向血管生成素样蛋白2阳性衰老细胞可改善成年雄性而非雌性动脉粥样硬化LDLr(-/-);hApoB(100)(+/+)小鼠的认知障碍。

期刊:Geroscience
影响因子:5.4
doi:10.1007/s11357-025-01763-x
Lambert, Mélanie; Miquel, Géraldine; Cagnone, Gael; Mury, Pauline; Villeneuve, Louis; Lesage, Frédéric; Thorin-Trescases, Nathalie; Thorin, Eric
心血管
神经科学
血管生成
衰老
细胞生物学
动脉粥样硬化
发表日期：2025
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Unconventional receptor functions and location-biased signaling of the lactate GPCR in the nucleus

乳酸GPCR在细胞核内的非常规受体功能和位置偏向性信号传导

期刊:Life Science Alliance
影响因子:2.9
doi:10.26508/lsa.202503226
Mohammad Nezhady, Mohammad Ali; Cagnone, Gael; Bajon, Emmanuel; Chaudhari, Prabhas; Modaresinejad, Monir; Hardy, Pierre; Maggiorani, Damien; Quiniou, Christiane; Joyal, Jean-Sébastien; Beauséjour, Christian; Chemtob, Sylvain
信号转导
细胞生物学
GPCR/Calcium/cAMP
发表日期：2025
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Timed topical dexamethasone eye drops improve mitochondrial function to prevent severe retinopathy of prematurity.

定时局部使用地塞米松滴眼液可改善线粒体功能，预防早产儿严重视网膜病变

期刊:Angiogenesis
影响因子:9.2
doi:10.1007/s10456-024-09948-2
Yagi Hitomi, Boeck Myriam, Petrishka-Lozenska Mariya, Lundgren Pia, Kasai Taku, Cagnone Gael, Neilsen Katherine, Wang Chaomei, Lee Jeff, Tomita Yohei, Singh Sasha A, Joyal Jean-Sébastien, Aikawa Masanori, Negishi Kazuno, Fu Zhongjie, Hellström Ann, Smith Lois E H
线粒体
发表日期：2024
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Corticosteroids reduce pathological angiogenesis yet compromise reparative vascular remodeling in a model of retinopathy.

皮质类固醇可减少病理性血管生成，但会损害视网膜病变模型中的修复性血管重塑

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2411640121
Hata Masayuki, Hata Maki, Dejda Agnieszka, Pilon Frédérique, Diaz-Marin Roberto, Fournier Frédérik, Joyal Jean-Sebastien, Cagnone Gael, Ochi Yotaro, Crespo-Garcia Sergio, Wilson Ariel M, Sapieha Przemyslaw
心血管
血管生成
发表日期：2024
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Senescence and Inflamm-Aging Are Associated With Endothelial Dysfunction in Men But Not Women With Atherosclerosis

衰老和炎症衰老与男性动脉粥样硬化患者的内皮功能障碍相关，但与女性动脉粥样硬化患者无关。

期刊:Jacc-Basic To Translational Science
影响因子:7.2
doi:10.1016/j.jacbts.2024.06.012
Mury, Pauline; Cagnone, Gael; Dagher, Olina; Wünnemann, Florian; Voghel, Guillaume; Beaudoin, Melissa; Lambert, Mélanie; Miquel, Géraldine; Noly, Pierre-Emmanuel; Perrault, Louis P; Carrier, Michel; Thorin-Trescases, Nathalie; Joyal, Jean-Sébastien; Lettre, Guillaume; Thorin, Eric
炎症
炎症/感染
Senescence
心血管
衰老
动脉粥样硬化
发表日期：2024
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Lack of HCAR1, the lactate GPCR, signaling promotes autistic-like behavior

乳酸G蛋白偶联受体（GPCR）HCAR1信号传导的缺失会促进类似自闭症的行为

期刊:Cell Communication and Signaling
影响因子:8.9
doi:10.1186/s12964-023-01188-z
Mohammad Nezhady, Mohammad Ali; Cagnone, Gael; Joyal, Jean-Sébastien; Chemtob, Sylvain
信号转导
自闭症
GPCR/Calcium/cAMP
神经科学
发表日期：2023
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Triglyceride-derived fatty acids reduce autophagy in a model of retinal angiomatous proliferation

甘油三酯衍生的脂肪酸可降低视网膜血管瘤增殖模型中的自噬作用

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.154174
Heckel, Emilie; Cagnone, Gael; Agnihotri, Tapan; Cakir, Bertan; Das, Ashim; Kim, Jin Sung; Kim, Nicholas; Lavoie, Geneviève; Situ, Anu; Pundir, Sheetal; Sun, Ye; Wünnemann, Florian; Pierce, Kerry A; Dennis, Courtney; Mitchell, Grant A; Chemtob, Sylvain; Rezende, Flavio A; Andelfinger, Gregor; Clish, Clary B; Roux, Philippe P; Sapieha, Przemyslaw; Smith, Lois Eh; Joyal, Jean-Sébastien
自噬
代谢
发表日期：2022
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Retinal glial remodeling by FGF21 preserves retinal function during photoreceptor degeneration

FGF21介导的视网膜胶质细胞重塑可在感光细胞退化过程中维持视网膜功能。

期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2021.102376
Fu, Zhongjie; Qiu, Chenxi; Cagnone, Gael; Tomita, Yohei; Huang, Shuo; Cakir, Bertan; Kotoda, Yumi; Allen, William; Bull, Edward; Akula, James D; Joyal, Jean-Sébastien; Hellström, Ann; Talukdar, Saswata; Smith, Lois E H
胶质细胞
FGF2
细胞生物学
FGF21
发表日期：2021
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