日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Hepatic GDP-fucose transporter SLC35C1 attenuates cholestatic liver injury and inflammation by inducing CEACAM1 N153 fucosylation.

肝脏 GDP-岩藻糖转运蛋白 SLC35C1 通过诱导 CEACAM1 N153 岩藻糖基化来减轻胆汁淤积性肝损伤和炎症

期刊:Hepatology
影响因子:15.8
doi:10.1097/HEP.0000000000001003
Zhang Liangjun, Xie Pingfan, Li Mingqiao, Zhang Xiaoxun, Fei Shuke, Zhao Nan, Li Ling, Xie Qiaoling, Xu Ziqian, Tang Wan, Zhu Guanyu, Zhu Zhixian, Xu Zuzhi, Li Jianwei, Zhang Chengcheng, Boyer James L, Chen Wensheng, Cai Shi-Ying, Pan Qiong, Chai Jin
毒理研究
肝损伤
CEACAM1
炎症
发表日期：2025
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Conjugated bile acid-driven CD14(+)CD16(+) monocyte infiltration promotes cholestatic liver injury by enhancing hepatocyte necroptosis

结合胆汁酸驱动的CD14(+)CD16(+)单核细胞浸润通过增强肝细胞坏死性凋亡促进胆汁淤积性肝损伤。

期刊:Jhep Reports
影响因子:7.5
doi:10.1016/j.jhepr.2025.101517
Zhu, Zhixian; Xu, Ziqian; Cao, Xinyu; Zhao, Nan; Lei, Jiaxin; Li, Ling; Li, Xi; Li, Yan; Li, Mingqiao; Ren, Tian; Liu, Li; Boyer, James L; Cai, Shi-Ying; Pan, Qiong; Zhang, Xiaoxun; Chai, Jin
CD16
CD14
凋亡
表观遗传
肝损伤
单核细胞
细胞生物学
毒理研究
发表日期：2025
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Liver Lymphatic Dysfunction as a Driver of Fibrosis and Cirrhosis Progression

肝脏淋巴功能障碍是纤维化和肝硬化进展的驱动因素

期刊:
影响因子:
doi:10.1101/2025.01.11.632552
Jeong, Jain; Hsu, Shao-Jung; Horikami, Daiki; Utsumi, Teruo; Yang, Yilin; Arefyev, Nikolai; Zhang, Xuchen; Cai, Shi-Ying; Boyer, James L; Garcia-Milan, Rolando; Tanaka, Masatake; McConnell, Matthew J; Huang, Hui-Chun; Iwakiri, Yasuko
肝硬化
发表日期：2025
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Hepatic TNFRSF12A promotes bile acid-induced hepatocyte pyroptosis through NFκB/Caspase-1/GSDMD signaling in cholestasis

肝脏TNFRSF12A通过NFκB/Caspase-1/GSDMD信号通路促进胆汁酸诱导的肝细胞焦亡（胆汁淤积）

期刊:Cell Death Discovery
影响因子:7
doi:10.1038/s41420-023-01326-z
Liao, Min; Liao, Junwei; Qu, Jiaquan; Shi, Pan; Cheng, Ying; Pan, Qiong; Zhao, Nan; Zhang, Xiaoxun; Zhang, Liangjun; Tan, Ya; Li, Qiao; Zhu, Jin-Fei; Li, Jianwei; Zhang, Chengcheng; Cai, Shi-Ying; Chai, Jin
表观遗传
DMD
GSDMD
信号转导
TNFRSF12A
焦亡
细胞生物学
发表日期：2023
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The role of the retinoid receptor, RAR/RXR heterodimer, in liver physiology

视黄酸受体RAR/RXR异二聚体在肝脏生理学中的作用

期刊:Biochimica et Biophysica Acta-Molecular Basis of Disease
影响因子:4.2
doi:10.1016/j.bbadis.2021.166085
Li, Baixue; Cai, Shi-Ying; Boyer, James L
信号转导
发表日期：2021
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The role of bile acids in cholestatic liver injury

胆汁酸在胆汁淤积性肝损伤中的作用

期刊:Annals of Translational Medicine
影响因子:
doi:10.21037/atm-20-5110
Cai, Shi-Ying; Boyer, James L
肝损伤
毒理研究
发表日期：2021
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Cenicriviroc, a cytokine receptor antagonist, potentiates all-trans retinoic acid in reducing liver injury in cholestatic rodents

塞尼西维罗是一种细胞因子受体拮抗剂，可增强全反式维甲酸在减轻胆汁淤积啮齿动物肝损伤方面的作用。

期刊:Liver International
影响因子:5.2
doi:10.1111/liv.13698
Yu, Dongke; Cai, Shi-Ying; Mennone, Albert; Vig, Pamela; Boyer, James L
信号转导
肝损伤
细胞生物学
毒理研究
免疫/内分泌
发表日期：2018
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Combination Therapy of All-Trans Retinoic Acid With Ursodeoxycholic Acid in Patients With Primary Sclerosing Cholangitis: A Human Pilot Study

全反式维甲酸联合熊去氧胆酸治疗原发性硬化性胆管炎患者的人体试验研究

期刊:Journal of Clinical Gastroenterology
影响因子:2.7
doi:10.1097/MCG.0000000000000591
Assis, David N; Abdelghany, Osama; Cai, Shi-Ying; Gossard, Andrea A; Eaton, John E; Keach, Jill C; Deng, Yanhong; Setchell, Kenneth D R; Ciarleglio, Maria; Lindor, Keith D; Boyer, James L
Human
发表日期：2017
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All-trans-retinoic acid improves cholestasis in α-naphthylisothiocyanate-treated rats and Mdr2-/- mice

全反式维甲酸可改善α-萘基异硫氰酸酯处理的大鼠和Mdr2-/-小鼠的胆汁淤积。

期刊:Journal of Pharmacology and Experimental Therapeutics
影响因子:3.8
doi:10.1124/jpet.113.209353
Cai, Shi-Ying; Mennone, Albert; Soroka, Carol J; Boyer, James L
Rat
发表日期：2014
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Altered expression and function of canalicular transporters during early development of cholestatic liver injury in Abcb4-deficient mice

Abcb4缺陷小鼠胆汁淤积性肝损伤早期发展过程中毛细胆管转运蛋白的表达和功能发生改变

期刊:American Journal of Physiology-Gastrointestinal and Liver Physiology
影响因子:3.3
doi:10.1152/ajpgi.00334.2013
Cai, Shi-Ying; Mennone, Albert; Soroka, Carol J; Boyer, James L
肝损伤
毒理研究
发表日期：2014
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