日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Neuraminidase 1 secondary deficiency contributes to CNS pathology in neurological mucopolysaccharidoses via brain protein hypersialylation

神经氨酸酶 1 继发性缺乏症通过脑蛋白过度唾液酸化作用导致神经系统粘多糖贮积症的中枢神经系统病变。

Xu, TianMeng; Heon-Roberts, Rachel; Moore, Travis; Dubot, Patricia; Pan, Xuefang; Guo, Tianlin; Cairo, Christopher W; Holley, Rebecca J; Bigger, Brian; Durcan, Thomas M; Levade, Thierry; Ausseil, Jerôme; Amilhon, Bénédicte; Gorelik, Alexei; Nagar, Bhushan; Khan, Shaukat; Tomatsu, Shunji; Sturiale, Luisa; Palmigiano, Angelo; Röckle, Iris; Thiesler, Hauke; Hildebrandt, Herbert; Garozzo, Domenico; Pshezhetsky, Alexey V

Secondary deficiency of neuraminidase 1 contributes to CNS pathology in neurological mucopolysaccharidoses via hypersialylation of brain glycoproteins

神经氨酸酶 1 的继发性缺乏通过脑糖蛋白的过度唾液酸化,导致神经系统粘多糖贮积症的中枢神经系统病变。

Xu, TianMeng; Heon-Roberts, Rachel; Moore, Travis; Dubot, Patricia; Pan, Xuefang; Guo, Tianlin; Cairo, Christopher W; Holley, Rebecca; Bigger, Brian; Durcan, Thomas M; Levade, Thierry; Ausseil, Jerôme; Amilhon, Bénédicte; Gorelik, Alexei; Nagar, Bhushan; Sturiale, Luisa; Palmigiano, Angelo; Röckle, Iris; Thiesler, Hauke; Hildebrandt, Herbert; Garozzo, Domenico; Pshezhetsky, Alexey V

Severe kidney dysfunction in sialidosis mice reveals an essential role for neuraminidase 1 in reabsorption

唾液酸沉积症小鼠的严重肾功能障碍揭示了神经氨酸酶1在重吸收过程中的重要作用

Kho, Ikhui; Demina, Ekaterina P; Pan, Xuefang; Londono, Irene; Cairo, Christopher W; Sturiale, Luisa; Palmigiano, Angelo; Messina, Angela; Garozzo, Domenico; Ung, Roth-Visal; Mac-Way, Fabrice; Bonneil, Éric; Thibault, Pierre; Lemaire, Mathieu; Morales, Carlos R; Pshezhetsky, Alexey V

Crystal structures of human lysosomal EPDR1 reveal homology with the superfamily of bacterial lipoprotein transporters

人类溶酶体EPDR1的晶体结构揭示了其与细菌脂蛋白转运蛋白超家族的同源性

Wei, Yong; Xiong, Zi Jian; Li, Jun; Zou, Chunxia; Cairo, Christopher W; Klassen, John S; Privé, Gilbert G

A quantitative, high-throughput method identifies protein-glycan interactions via mass spectrometry

一种定量、高通量的方法通过质谱分析鉴定蛋白质-聚糖相互作用

Kitov, Pavel I; Kitova, Elena N; Han, Ling; Li, Zhixiong; Jung, Jaesoo; Rodrigues, Emily; Hunter, Carmanah D; Cairo, Christopher W; Macauley, Matthew S; Klassen, John S

New Answers to Old Conundrums: What Antibodies, Exosomes and Inflammasomes Bring to the Conversation. Canadian National Transplant Research Program International Summit Report

旧难题的新答案:抗体、外泌体和炎症小体为讨论带来什么?加拿大国家移植研究项目国际峰会报告

Dieudé, Mélanie; West, Lori J; Muruve, Daniel A; Gunaratnam, Lakshman; Mohanakumar, Thalachallour; Zorn, Emmanuel; Cairo, Christopher W; Freed, Darren H; Schultz, Kirk R; Fairchild, Robert L; Hébert, Marie-Josée

Galectin-3 alters the lateral mobility and clustering of β1-integrin receptors

半乳糖凝集素-3改变β1整合素受体的侧向迁移和聚集

Yang, Esther H; Rode, Julia; Howlader, Md Amran; Eckermann, Marina; Santos, Jobette T; Hernandez Armada, Daniel; Zheng, Ruixiang; Zou, Chunxia; Cairo, Christopher W

Enhanced Cross-Linking of Diazirine-Modified Sialylated Glycoproteins Enabled through Profiling of Sialidase Specificities

通过唾液酸酶特异性分析增强重氮丙烯修饰的唾液酸化糖蛋白的交联

McCombs, Janet E; Zou, Chunxia; Parker, Randy B; Cairo, Christopher W; Kohler, Jennifer J

Detection of Diffusion Heterogeneity in Single Particle Tracking Trajectories Using a Hidden Markov Model with Measurement Noise Propagation

利用隐马尔可夫模型和测量噪声传播检测单粒子追踪轨迹中的扩散异质性

Slator, Paddy J; Cairo, Christopher W; Burroughs, Nigel J

Structural basis for substrate specificity of mammalian neuraminidases

哺乳动物神经氨酸酶底物特异性的结构基础

Smutova, Victoria; Albohy, Amgad; Pan, Xuefang; Korchagina, Elena; Miyagi, Taeko; Bovin, Nicolai; Cairo, Christopher W; Pshezhetsky, Alexey V