日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Mechanism for Statin-Induced Susceptibility to Myopathy

他汀类药物诱发肌病的机制

Sabine Lotteau, Niklas Ivarsson, Zhaokang Yang, Damien Restagno, John Colyer, Philip Hopkins, Andrew Weightman, Koichi Himori, Takashi Yamada, Joseph Bruton, Derek Steele, Håkan Westerblad, Sarah Calaghan

Beta1-adrenoceptor antagonist, metoprolol attenuates cardiac myocyte Ca(2+) handling dysfunction in rats with pulmonary artery hypertension

β1-肾上腺素能受体拮抗剂美托洛尔可减轻肺动脉高压大鼠心肌细胞Ca2+处理功能障碍。

Fowler, Ewan D; Drinkhill, Mark J; Norman, Ruth; Pervolaraki, Eleftheria; Stones, Rachel; Steer, Emma; Benoist, David; Steele, Derek S; Calaghan, Sarah C; White, Ed

Simvastatin Promotes Cardiac Myocyte Relaxation in Association with Phosphorylation of Troponin I

辛伐他汀与肌钙蛋白 I 磷酸化相关促进心肌细胞松弛

David A MacDougall, Sara D Pugh, Harpreet S Bassi, Sabine Lotteau, Karen E Porter, Sarah Calaghan

Caveolae in Rabbit Ventricular Myocytes: Distribution and Dynamic Diminution after Cell Isolation

兔心室肌细胞中的小窝:分布及细胞分离后的动态减少

Burton, Rebecca A B; Rog-Zielinska, Eva A; Corbett, Alexander D; Peyronnet, Rémi; Bodi, Ilona; Fink, Martin; Sheldon, Judith; Hoenger, Andreas; Calaghan, Sarah C; Bub, Gil; Kohl, Peter

Identification of caveolar resident proteins in ventricular myocytes using a quantitative proteomic approach: dynamic changes in caveolar composition following adrenoceptor activation

使用定量蛋白质组学方法鉴定心室肌细胞中的洞穴驻留蛋白:肾上腺素能受体激活后洞穴组成的动态变化

Krzysztof J Wypijewski, Michele Tinti, Wenzhang Chen, Douglas Lamont, Michael L J Ashford, Sarah C Calaghan, William Fuller

Cellular Hypertrophy and Increased Susceptibility to Spontaneous Calcium-Release of Rat Left Atrial Myocytes Due to Elevated Afterload

后负荷增加导致大鼠左心房肌细胞肥大和自发性钙释放敏感性增加

Haifei Zhang, Mark B Cannell, Shang Jin Kim, Judy J Watson, Ruth Norman, Sarah C Calaghan, Clive H Orchard, Andrew F James

The Golgi apparatus is a functionally distinct Ca2+ store regulated by the PKA and Epac branches of the β1-adrenergic signaling pathway

高尔基体是一个功能独特的 Ca2+ 储存器,受 β1-肾上腺素能信号通路的 PKA 和 Epac 分支调控

Zhaokang Yang, Hannah M Kirton, David A MacDougall, John P Boyle, James Deuchars, Brenda Frater, Sreenivasan Ponnambalam, Matthew E Hardy, Edward White, Sarah C Calaghan, Chris Peers, Derek S Steele

Caveolin contributes to the modulation of basal and β-adrenoceptor stimulated function of the adult rat ventricular myocyte by simvastatin: a novel pleiotropic effect

Caveolin 有助于辛伐他汀调节成年大鼠心室肌细胞的基础和 β 肾上腺素能受体刺激功能:一种新的多效性作用

Sara D Pugh, David A MacDougall, Shailesh R Agarwal, Robert D Harvey, Karen E Porter, Sarah Calaghan

Regulation of the cardiac sodium pump

心脏钠泵的调节

Fuller, W; Tulloch, L B; Shattock, M J; Calaghan, S C; Howie, J; Wypijewski, K J

Caveolae compartmentalise β2-adrenoceptor signals by curtailing cAMP production and maintaining phosphatase activity in the sarcoplasmic reticulum of the adult ventricular myocyte

在成年心室肌细胞中,小窝通过抑制 cAMP 的产生和维持肌浆网中的磷酸酶活性来分隔 β2-肾上腺素能受体信号。

Macdougall, David A; Agarwal, Shailesh R; Stopford, Elizabeth A; Chu, Hongjin; Collins, Jennifer A; Longster, Anna L; Colyer, John; Harvey, Robert D; Calaghan, Sarah