日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Androgen deprivation-mediated activation of AKT is enhanced in prostate cancer with TMPRSS2:ERG fusion.

在具有 TMPRSS2:ERG 融合的前列腺癌中,雄激素剥夺介导的 AKT 激活增强。

Ma Fen, Chen Sen, Cecchi Luigi, Ersoy-Fazlioglu Betul, Russo Joshua W, Arai Seiji, Awad Seifeldin, Calagua Carla, Xie Fang, Poluben Larysa, Voznesensky Olga, Ku Anson T, Karzai Fatima, Cai Changmeng, Einstein David J, Ye Huihui, Yuan Xin, Toker Alex, Taplin Mary-Ellen, Sowalsky Adam G, Balk Steven P

Increased ErbB2 Signaling Is an Early Adaptation to Androgen Signaling Inhibition and Persists in Castration-Resistant Prostate Cancer

ErbB2信号增强是雄激素信号抑制的早期适应性反应,并在去势抵抗性前列腺癌中持续存在。

Jude Owiredu #,Betul Ersoy-Fazlioglu #,Larysa Poluben #,Carla Calagua,Christopher Dennehy,Anastasia-Maria Stavridi,Liyang Wang,Olga Voznesensky,Fang Xie,Huihui Ye,Yue Sun,David J Einstein,Xin Gao,Charlene Mantia,Mary-Ellen Taplin,William J Muller,Steven P Balk,Joshua W Russo

Consultation-Liaison Case Conference: Suicidal Ideation in a Patient at the End-of-Life

会诊联络病例研讨会:临终患者的自杀意念

Calagua-Bedoya, Eduardo Andres; Ernst, Carrie; Shalev, Daniel; Bialer, Philip

Autocrine Canonical Wnt Signaling Primes Noncanonical Signaling through ROR1 in Metastatic Castration-Resistant Prostate Cancer

在转移性去势抵抗性前列腺癌中,自分泌经典 Wnt 信号通过 ROR1 启动非经典信号

Fen Ma, Seiji Arai, Keshan Wang, Carla Calagua, Amanda R Yuan, Larysa Poluben, Zhongkai Gu, Joshua W Russo, David J Einstein, Huihui Ye, Meng Xiao He, Yu Liu, Eliezer Van Allen, Adam G Sowalsky, Manoj K Bhasin, Xin Yuan, Steven P Balk

Collision tumors revealed by prospectively assessing subtype-defining molecular alterations in 904 individual prostate cancer foci

通过前瞻性评估 904 个前列腺癌病灶中定义亚型的分子改变来揭示碰撞肿瘤

Jacqueline Fontugne, Peter Y Cai, Hussein Alnajar, Bhavneet Bhinder, Kyung Park, Huihui Ye, Shaham Beg, Verena Sailer, Javed Siddiqui, Mirjam Blattner-Johnson, Jaclyn A Croyle, Zohal Noorzad, Carla Calagua, Theresa Y MacDonald, Ulrika Axcrona, Mari Bogaard, Karol Axcrona, Douglas S Scherr, Martin G

EZH2 inhibition activates a dsRNA-STING-interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer

EZH2 抑制可激活 dsRNA-STING-干扰素应激轴,从而增强前列腺癌对 PD-1 检查点阻断的反应

Katherine L Morel #, Anjali V Sheahan #, Deborah L Burkhart, Sylvan C Baca, Nadia Boufaied, Yin Liu, Xintao Qiu, Israel Cañadas, Kevin Roehle, Max Heckler, Carla Calagua, Huihui Ye, Constantia Pantelidou, Phillip Galbo, Sukanya Panja, Antonina Mitrofanova, Scott Wilkinson, Nichelle C Whitlock, Shana

A Subset of Localized Prostate Cancer Displays an Immunogenic Phenotype Associated with Losses of Key Tumor Suppressor Genes

部分局限性前列腺癌表现出免疫原性表型,该表型与关键抑癌基因的缺失有关。

Calagua, Carla; Ficial, Miriam; Jansen, Caroline S; Hirz, Taghreed; Del Balzo, Luke; Wilkinson, Scott; Lake, Ross; Ku, Anson T; Voznesensky, Olga; Sykes, David B; Saylor, Philip J; Ye, Huihui; Signoretti, Sabina; Kissick, Haydn; Sowalsky, Adam G; Balk, Steven P; Einstein, David J

Results of a Randomized Phase II Trial of Intense Androgen Deprivation Therapy prior to Radical Prostatectomy in Men with High-Risk Localized Prostate Cancer

一项随机II期临床试验的结果显示,在根治性前列腺切除术前对高危局限性前列腺癌患者进行强化雄激素剥夺疗法。

McKay, Rana R; Xie, Wanling; Ye, Huihui; Fennessy, Fiona M; Zhang, Zhenwei; Lis, Rosina; Calagua, Carla; Rathkopf, Dana; Laudone, Vincent P; Bubley, Glenn J; Einstein, David J; Chang, Peter K; Wagner, Andrew A; Parsons, J Kellogg; Preston, Mark A; Kilbridge, Kerry; Chang, Steven L; Choudhury, Atish D; Pomerantz, Mark M; Trinh, Quoc-Dien; Kibel, Adam S; Taplin, Mary-Ellen

Metastatic Castration-Resistant Prostate Cancer Remains Dependent on Oncogenic Drivers Found in Primary Tumors

转移性去势抵抗性前列腺癌仍然依赖于原发肿瘤中发现的致癌驱动因子

Einstein, David J; Arai, Seiji; Calagua, Carla; Xie, Fang; Voznesensky, Olga; Capaldo, Brian J; Luffman, Christina; Hecht, Jonathan L; Balk, Steven P; Sowalsky, Adam G; Russo, Joshua W

Phosphorylation of the androgen receptor at Ser81 is co-sustained by CDK1 and CDK9 and leads to AR-mediated transactivation in prostate cancer

CDK1 和 CDK9 共同维持雄激素受体 Ser81 位点的磷酸化,并导致前列腺癌中 AR 介导的转录激活

XinTao Gao, Jiaqian Liang, LiYang Wang, Zhaoyang Zhang, Penghui Yuan, Jiaxin Wang, Yanfei Gao, Fen Ma, Carla Calagua, Huihui Ye, Olga Voznesensky, Shaogang Wang, Tao Wang, Jihong Liu, Shaoyong Chen, Xiaming Liu