日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
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2025
2026
影响因子:
–

A spatial atlas of the complement system uncovers unique expression patterns in postnatal brain development in mice

补体系统的空间图谱揭示了小鼠出生后大脑发育中独特的表达模式

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-66048-5
Zhang, Yingying; Watson, Brianna; Rattan, Ajitanuj; Lee, Tyrone; Chawla, Smriti; Geistlinger, Ludwig; Guan, Yilin; Lord, Finley B; Ma, Minghe; Miwa, Takashi; Golla, Madhu; Caldarone, Barbara J; Song, Wen-Chao; Moffitt, Jeffrey R; Carroll, Michael C
发育与干细胞
神经科学
免疫/内分泌
发表日期：2025
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Inhibition of hippocampal mossy fiber plasticity and episodic memory by human Aβ oligomers is prevented by enhancing cAMP signaling in Alzheimer's mice.

人类 Aβ 寡聚体对海马苔状纤维可塑性和情景记忆的抑制作用可通过增强阿尔茨海默病小鼠的 cAMP 信号传导来阻止

期刊:Alzheimers & Dementia
影响因子:11.1
doi:10.1002/alz.70194
Jin Shan-Xue, Bellier Jean-Pierre, Wells Adrienne, LIopis Paula Montero, Anekal Praju Vikas, Tresback Jason S, Caldarone Barbara J, Liu Lei, Li Shaomin, Dettmer Ulf, Ramalingam Nagendran, Selkoe Dennis J
信号转导
Human
发表日期：2025
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Gabrb3 endothelial cell-specific knockout mice display abnormal blood flow, hypertension, and behavioral dysfunction

Gabrb3 内皮细胞特异性敲除小鼠表现出血流异常、高血压和行为功能障碍

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-022-08806-9
Agrud, Anass; Subburaju, Sivan; Goel, Pranay; Ren, Jun; Kumar, Ashwin Srinivasan; Caldarone, Barbara J; Dai, Wangde; Chavez, Jesus; Fukumura, Dai; Jain, Rakesh K; Kloner, Robert A; Vasudevan, Anju
细胞生物学
内皮细胞
心血管
高血压
发表日期：2022
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Cis P-tau underlies vascular contribution to cognitive impairment and dementia and can be effectively targeted by immunotherapy in mice

顺式磷酸化tau蛋白是血管因素导致认知障碍和痴呆的基础，并且可以作为小鼠免疫疗法的有效靶点。

期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.aaz7615
Qiu, Chenxi; Albayram, Onder; Kondo, Asami; Wang, Bin; Kim, Nami; Arai, Ken; Tsai, Cheng-Yu; Bassal, Mahmoud A; Herbert, Megan K; Washida, Kazuo; Angeli, Peter; Kozono, Shingo; Stucky, Joseph E; Baxley, Sean; Lin, Yu-Min; Sun, Yan; Rotenberg, Alexander; Caldarone, Barbara J; Bigio, Eileen H; Chen, Xiaochun; Tenen, Daniel G; Zeidel, Mark; Lo, Eng H; Zhou, Xiao Zhen; Lu, Kun Ping
信号转导
磷酸化
神经科学
免疫/内分泌
发表日期：2021
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Effector function of anti-pyroglutamate-3 Aβ antibodies affects cognitive benefit, glial activation and amyloid clearance in Alzheimer's-like mice

抗焦谷氨酸-3 Aβ抗体的效应功能影响阿尔茨海默病样小鼠的认知功能、胶质细胞活化和淀粉样蛋白清除。

期刊:Alzheimers Research & Therapy
影响因子:7.6
doi:10.1186/s13195-019-0579-8
Crehan, Helen; Liu, Bin; Kleinschmidt, Martin; Rahfeld, Jens-Ulrich; Le, Kevin X; Caldarone, Barbara J; Frost, Jeffrey L; Hettmann, Thore; Hutter-Paier, Birgit; O'Nuallain, Brian; Park, Mi-Ae; DiCarli, Marcelo F; Lues, Inge; Schilling, Stephan; Lemere, Cynthia A
胶质细胞
阿尔茨海默症
神经科学
细胞生物学
发表日期：2020
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Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice

补体C3缺乏可保护老年富含斑块的APP/PS1小鼠免受神经退行性变的影响

期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.aaf6295
Shi, Qiaoqiao; Chowdhury, Saba; Ma, Rong; Le, Kevin X; Hong, Soyon; Caldarone, Barbara J; Stevens, Beth; Lemere, Cynthia A
APP
神经科学
免疫/内分泌
发表日期：2017
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Zebrafish behavioral profiling identifies multitarget antipsychotic-like compounds

斑马鱼行为分析鉴定出多靶点抗精神病样化合物

期刊:Nature Chemical Biology
影响因子:13.7
doi:10.1038/nchembio.2097
Bruni, Giancarlo; Rennekamp, Andrew J; Velenich, Andrea; McCarroll, Matthew; Gendelev, Leo; Fertsch, Ethan; Taylor, Jack; Lakhani, Parth; Lensen, Dennis; Evron, Tama; Lorello, Paul J; Huang, Xi-Ping; Kolczewski, Sabine; Carey, Galen; Caldarone, Barbara J; Prinssen, Eric; Roth, Bryan L; Keiser, Michael J; Peterson, Randall T; Kokel, David
发表日期：2016
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An anti-pyroglutamate-3 Aβ vaccine reduces plaques and improves cognition in APPswe/PS1ΔE9 mice

抗焦谷氨酸-3 Aβ疫苗可减少APPswe/PS1ΔE9小鼠的斑块并改善其认知功能。

期刊:Neurobiology of Aging
影响因子:3.5
doi:10.1016/j.neurobiolaging.2015.08.021
Frost, Jeffrey L; Liu, Bin; Rahfeld, Jens-Ulrich; Kleinschmidt, Martin; O'Nuallain, Brian; Le, Kevin X; Lues, Inge; Caldarone, Barbara J; Schilling, Stephan; Demuth, Hans-Ulrich; Lemere, Cynthia A
APP
神经科学
发表日期：2015
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Dissociation between duration of action in the forced swim test in mice and nicotinic acetylcholine receptor occupancy with sazetidine, varenicline, and 5-I-A85380

沙泽替丁、伐尼克兰和 5-I-A85380 在小鼠强迫游泳试验中的作用持续时间与尼古丁乙酰胆碱受体占有率之间的分离

期刊:Psychopharmacology
影响因子:3.3
doi:10.1007/s00213-011-2271-y
Caldarone, Barbara J; Wang, Daguang; Paterson, Neil E; Manzano, Michael; Fedolak, Allison; Cavino, Katie; Kwan, Mei; Hanania, Taleen; Chellappan, Sheela K; Kozikowski, Alan P; Olivier, Berend; Picciotto, Marina R; Ghavami, Afshin
信号转导
发表日期：2011
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RGS9-2: probing an intracellular modulator of behavior as a drug target

RGS9-2：探索细胞内行为调节因子作为药物靶点

期刊:Trends in Pharmacological Sciences
影响因子:19.9
doi:10.1016/j.tips.2008.11.006
Traynor, John R; Terzi, Dimitra; Caldarone, Barbara J; Zachariou, Venetia
细胞生物学
发表日期：2009
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