日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

NHE3 inhibitor tenapanor maintains intestinal barrier function, decreases visceral hypersensitivity, and attenuates TRPV1 signaling in colonic sensory neurons

NHE3抑制剂替那帕诺可维持肠道屏障功能，降低内脏高敏感性，并减弱结肠感觉神经元中的TRPV1信号传导。

期刊:American Journal of Physiology-Gastrointestinal and Liver Physiology
影响因子:3.3
doi:10.1152/ajpgi.00233.2023
King, Andrew J; Chang, Lin; Li, Qian; Liu, Liansheng; Zhu, Yaohui; Pasricha, Pankaj J; Wang, Ji; Siegel, Matthew; Caldwell, Jeremy S; Edelstein, Susan; Rosenbaum, David P; Kozuka, Kenji
信号转导
TRPV1
神经科学
发表日期：2024
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Modeling the Kinetics of Lipid-Nanoparticle- Mediated Delivery of Multiple siRNAs to Evaluate the Effect on Competition for Ago2

通过模拟脂质纳米颗粒介导的多siRNA递送动力学，评估其对Ago2竞争的影响

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.1
doi:10.1016/j.omtn.2019.03.004
Mihaila, Radu; Ruhela, Dipali; Galinski, Beverly; Card, Ananda; Cancilla, Mark; Shadel, Timothy; Kang, Jing; Tep, Samnang; Wei, Jie; Haas, R Matthew; Caldwell, Jeremy; Flanagan, W Michael; Kuklin, Nelly; Cherkaev, Elena; Ason, Brandon
发表日期：2019
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Development and Characterization of a Human and Mouse Intestinal Epithelial Cell Monolayer Platform

人源和鼠源肠上皮细胞单层平台的建立和表征

期刊:Stem Cell Reports
影响因子:5.1
doi:10.1016/j.stemcr.2017.10.013
Kozuka, Kenji; He, Ying; Koo-McCoy, Samantha; Kumaraswamy, Padmapriya; Nie, Baoming; Shaw, Karen; Chan, Priscilla; Leadbetter, Michael; He, Limin; Lewis, Jason G; Zhong, Ziyang; Charmot, Dominique; Balaa, Marwan; King, Andrew J; Caldwell, Jeremy S; Siegel, Matthew
上皮细胞
细胞生物学
Mouse
Human
发表日期：2017
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Rescue of Mtp siRNA-induced hepatic steatosis by DGAT2 siRNA silencing.

通过DGAT2 siRNA沉默挽救Mtp siRNA诱导的肝脂肪变性

期刊:Journal of Lipid Research
影响因子:4.1
doi:10.1194/jlr.M021063
Tep Samnang, Mihaila Radu, Freeman Alexander, Pickering Victoria, Huynh Felicia, Tadin-Strapps Marija, Stracks Allison, Hubbard Brian, Caldwell Jeremy, Flanagan W Michael, Kuklin Nelly A, Ason Brandon
DGAT2
发表日期：2012
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HTS-Compatible Patient-Derived Cell-Based Assay to Identify Small Molecule Modulators of Aberrant Splicing in Myotonic Dystrophy Type 1.

适用于高通量筛选的患者来源细胞检测方法，用于鉴定 1 型强直性肌营养不良症中异常剪接的小分子调节剂

期刊:
影响因子:
doi:10.2174/1875397301004010009
O'Leary Debra A, Vargas Leonardo, Sharif Orzala, Garcia Michael E, Sigal Yury J, Chow Siu-Kei, Schmedt Christian, Caldwell Jeremy S, Brinker Achim, Engels Ingo H
细胞生物学
发表日期：2010
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Identification of small molecule and genetic modulators of AON-induced dystrophin exon skipping by high-throughput screening

利用高通量筛选鉴定AON诱导的肌营养不良蛋白外显子跳跃的小分子和基因调节剂

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0008348
O'Leary, Debra A; Sharif, Orzala; Anderson, Paul; Tu, Buu; Welch, Genevieve; Zhou, Yingyao; Caldwell, Jeremy S; Engels, Ingo H; Brinker, Achim
发表日期：2009
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