GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28- CD8+ T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppression
单倍体相合移植后移植物抗宿主病:一种新型的、MHC定义的恒河猴模型发现,在共刺激阻断和基于西罗莫司的免疫抑制治疗期间,CD28-CD8+T细胞是突破性T细胞增殖的储存库
期刊:Blood
影响因子:23.1
doi:10.1182/blood-2010-06-289272
Miller, Weston P; Srinivasan, Swetha; Panoskaltsis-Mortari, Angela; Singh, Karnail; Sen, Sharon; Hamby, Kelly; Deane, Taylor; Stempora, Linda; Beus, Jonathan; Turner, Alexa; Wheeler, Caleb; Anderson, Daniel C; Sharma, Prachi; Garcia, Anapatricia; Strobert, Elizabeth; Elder, Eric; Crocker, Ian; Crenshaw, Timothy; Penedo, M Cecilia T; Ward, Thea; Song, Mingqing; Horan, John; Larsen, Christian P; Blazar, Bruce R; Kean, Leslie S
T细胞
CD8
T细胞
细胞生物学
CD2
CD28
免疫/内分泌