日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Increased TMEM106B levels lead to lysosomal dysfunction which affects synaptic signaling and neuronal health.

TMEM106B 水平升高会导致溶酶体功能障碍,从而影响突触信号传导和神经元健康

Perneel Jolien, Lastra Osua Miranda, Alidadiani Sara, Peeters Nele, De Witte Linus, Heeman Bavo, Manzella Simona, De Rycke Riet, Brooks Mieu, Perkerson Ralph B, Calus Elke, De Coster Wouter, Neumann Manuela, Mackenzie Ian R A, Van Dam Debby, Asselbergh Bob, Ellender Tommas, Zhou Xiaolai, Rademakers Rosa

AAV-Based Intracerebral Administration of BDNF Promotes Myelin Repair and Cognitive Improvement After Cuprizone-Induced Demyelination.

基于 AAV 的脑内注射 BDNF 可促进铜唑诱导脱髓鞘后的髓鞘修复和认知功能改善。

El Ouaamari Yousra, Ricciardi Leonardo, van der Heijden Sanne, Peter Antonia, De Waele Jorrit, Van den Bos Jasper, Van Dam Debby, Calus Elke, Kuhn Sarah, Marei Waleed, Dombrowski Yvonne, Verhoye Marleen, Ponsaerts Peter, Wens Inez, Cools Nathalie

Long-Term Pharmacological Inhibition of the Activity of All NOS Isoforms Rather Than Genetic Knock-Out of Endothelial NOS Leads to Impaired Spatial Learning and Memory in C57BL/6 Mice

长期药理学抑制所有NOS同工酶的活性,而非基因敲除内皮型NOS,会导致C57BL/6小鼠空间学习和记忆能力受损。

Hendrickx, Jhana O; De Moudt, Sofie; Calus, Elke; De Deyn, Peter Paul; Van Dam, Debby; De Meyer, Guido R Y