日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Epigenetic therapy sensitizes anti-PD-1 refractory head and neck cancers to immunotherapy rechallenge.

表观遗传疗法可使对PD-1抗体耐药的头颈癌对免疫疗法再次治疗敏感

Qin Tingting, Mattox Austin K, Campbell Jean S, Park Jong Chul, Shin Kee-Young, Li Shiting, Sadow Peter M, Faquin William C, Micevic Goran, Daniels Andrew J, Haddad Robert, Garris Christopher S, Pittet Mikael J, Mempel Thorsten R, ONeill Anne, Sartor Maureen A, Pai Sara I

Transcriptional and functional analyses of neoantigen-specific CD4 T cells during a profound response to anti-PD-L1 in metastatic Merkel cell carcinoma

转移性默克尔细胞癌中抗PD-L1治疗强烈反应期间新抗原特异性CD4 T细胞的转录和功能分析

Church, Candice; Pulliam, Thomas; Longino, Natalie; Park, Song Y; Smythe, Kimberly S; Makarov, Vladimir; Riaz, Nadeem; Jing, Lichen; Amezquita, Robert; Campbell, Jean S; Gottardo, Raphael; Pierce, Robert H; Choi, Jaehyuk; Chan, Timothy A; Koelle, David M; Nghiem, Paul

Neoadjuvant Therapy Induces a Potent Immune Response to Sarcoma, Dominated by Myeloid and B Cells

新辅助疗法可诱导针对肉瘤的强效免疫反应,该反应以髓系细胞和B细胞为主。

Goff, Peter H; Riolobos, Laura; LaFleur, Bonnie J; Spraker, Matthew B; Seo, Y David; Smythe, Kimberly S; Campbell, Jean S; Pierce, Robert H; Zhang, Yuzheng; He, Qianchuan; Kim, Edward Y; Schaub, Stephanie K; Kane, Gabrielle M; Mantilla, Jose G; Chen, Eleanor Y; Ricciotti, Robert; Thompson, Matthew J; Cranmer, Lee D; Wagner, Michael J; Loggers, Elizabeth T; Jones, Robin L; Murphy, Erin; Blumenschein, Wendy M; McClanahan, Terrill K; Earls, Jon; Flanagan, Kevin C; LaFranzo, Natalie A; Kim, Teresa S; Pollack, Seth M

Immunologic Gene Signature Analysis Correlates Myeloid Cells and M2 Macrophages with Time to Trabectedin Failure in Sarcoma Patients

免疫基因特征分析表明,髓系细胞和M2巨噬细胞与肉瘤患者曲贝替定治疗失败时间相关

Schroeder, Brett A; Zhang, Yuzheng; Smythe, Kimberly S; Desai, Parth; Thomas, Anish; Viveiros, Pedro; Alexiev, Borislav A; Obeidin, Farres; Chen, Eleanor Y; Cranmer, Lee D; Wagner, Michael J; Jones, Robin L; Campbell, Jean S; Pierce, Robert H; He, Qianchuan; Pollack, Seth M

Mavorixafor, an Orally Bioavailable CXCR4 Antagonist, Increases Immune Cell Infiltration and Inflammatory Status of Tumor Microenvironment in Patients with Melanoma

口服生物利用度高的CXCR4拮抗剂Mavorixafor可增加黑色素瘤患者肿瘤微环境的免疫细胞浸润和炎症状态。

Andtbacka, Robert H I; Wang, Yan; Pierce, Robert H; Campbell, Jean S; Yushak, Melinda; Milhem, Mohammed; Ross, Merrick; Niland, Katie; Arbeit, Robert D; Parasuraman, Sudha; Bickley, Kris; Yeung, Cecilia Cs; Aicher, Lauri D; Smythe, Kimberly S; Gan, Lu

Human Papillomavirus-Directed Therapeutics for Human Papillomavirus-Associated Oropharyngeal Cancer

针对人乳头瘤病毒相关口咽癌的人乳头瘤病毒靶向治疗

Campbell, Jean S; Pai, Sara I

CD4+ T cell and M2 macrophage infiltration predict dedifferentiated liposarcoma patient outcomes

CD4+ T细胞和M2巨噬细胞浸润可预测去分化脂肪肉瘤患者的预后。

Schroeder, Brett A; LaFranzo, Natalie A; LaFleur, Bonnie J; Gittelman, Rachel M; Vignali, Marissa; Zhang, Shihong; Flanagan, Kevin C; Rytlewski, Julie; Riolobos, Laura; Schulte, Brian C; Kim, Teresa S; Chen, Eleanor; Smythe, Kimberly S; Wagner, Michael J; Mantilla, Jose G; Campbell, Jean S; Pierce, Robert H; Jones, Robin L; Cranmer, Lee D; Pollack, Seth M

Intratumoral delivery of an HPV vaccine elicits a broad anti-tumor immune response that translates into a potent anti-tumor effect in a preclinical murine HPV model

瘤内注射HPV疫苗可诱导广泛的抗肿瘤免疫反应,并在临床前小鼠HPV模型中转化为强效的抗肿瘤效果。

Ishida, Eiichi; Lee, Jina; Campbell, Jean S; Chakravarty, Patrick D; Katori, Yukio; Ogawa, Takenori; Johnson, Lauren; Mukhopadhyay, Anandaroop; Faquin, William C; Lin, Derrick T; Wirth, Lori J; Pierce, Robert H; Pai, Sara I

Branched-chain amino acids prevent hepatic fibrosis and development of hepatocellular carcinoma in a non-alcoholic steatohepatitis mouse model

支链氨基酸可预防非酒精性脂肪性肝炎小鼠模型中的肝纤维化和肝细胞癌的发生。

Takegoshi, Kai; Honda, Masao; Okada, Hikari; Takabatake, Riuta; Matsuzawa-Nagata, Naoto; Campbell, Jean S; Nishikawa, Masashi; Shimakami, Tetsuro; Shirasaki, Takayoshi; Sakai, Yoshio; Yamashita, Taro; Takamura, Toshinari; Tanaka, Takuji; Kaneko, Shuichi

Role of Smad3 in platelet-derived growth factor-C-induced liver fibrosis

Smad3在血小板衍生生长因子C诱导的肝纤维化中的作用

Lee, Jung Il; Wright, Jocelyn H; Johnson, Melissa M; Bauer, Renay L; Sorg, Kristina; Yuen, Sebastian; Hayes, Brian J; Nguyen, Lananh; Riehle, Kimberly J; Campbell, Jean S