Canalis Ernesto相关文献与解析，生知库 | 链接生命科学的每一步

NOTCH2 disrupts the synovial fibroblast identity and the inflammatory response of epiphyseal chondrocytes

NOTCH2 会破坏滑膜成纤维细胞的特性以及骨骺软骨细胞的炎症反应。

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1016/j.jbc.2025.110206

Canalis, Ernesto; Guzzo, Rosa; Schilling, Lauren; Denker, Emily

A NOTCH3 pathogenic variant influences osteogenesis and can be targeted by antisense oligonucleotides in induced pluripotent stem cells

NOTCH3致病变异会影响成骨作用，并且可以通过诱导多能干细胞中的反义寡核苷酸进行靶向治疗。

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0316644

Canalis, Ernesto; Yu, Jungeun; Schilling, Lauren; Jafar-Nejad, Paymaan; Carrer, Michele

A NOTCH2 pathogenic variant and HES1 regulate osteoclastogenesis in induced pluripotent stem cells

NOTCH2致病变异体和HES1调控诱导多能干细胞中的破骨细胞生成

期刊:

影响因子:

doi:10.1016/j.bone.2024.117334

Canalis, Ernesto; Schilling, Lauren; Denker, Emily; Stoddard, Christopher; Yu, Jungeun

Role of Metformin in Improving Non-Union Bone Fracture Healing in a Diabetic Rat Model

二甲双胍在改善糖尿病大鼠模型骨不连骨折愈合中的作用

期刊:Endocrine Reviews

影响因子:22

doi:10.1210/er.2007-0036

Giustina, Andrea; Mazziotti, Gherardo; Canalis, Ernesto; Cain, Jarrett D; Zhang, Jianying; Hogan, Macalus V; H-C. Wang, James

TNFα has differential effects on the transcriptome profile of selected populations in murine cartilage

TNFα对小鼠软骨中特定细胞群的转录组谱具有不同的影响

期刊:Osteoarthritis and Cartilage Open

影响因子:2.8

doi:10.1016/j.ocarto.2024.100528

Canalis, Ernesto; Schilling, Lauren; Denker, Emily

Induced pluripotent stem cell technology in bone biology

诱导多能干细胞技术在骨生物学中的应用

期刊:

影响因子:

doi:10.1016/j.bone.2023.116760

Kidwai, Fahad K; Canalis, Ernesto; Robey, Pamela G

Antisense oligonucleotides targeting a NOTCH3 mutation in male mice ameliorate the cortical osteopenia of lateral meningocele syndrome

针对雄性小鼠 NOTCH3 突变的反义寡核苷酸可改善侧脑膜膨出综合征的皮质骨减少症。

期刊:

影响因子:

doi:10.1016/j.bone.2023.116898

Canalis, Ernesto; Mocarska, Magda; Schilling, Lauren; Jafar-Nejad, Paymaan; Carrer, Michele

Role of Notch signaling in corticalization

Notch信号在皮层化中的作用

Inactivation of Hes1 in Skeletal Undifferentiated Cells Increases Bone Volume

骨骼未分化细胞中Hes1的失活会增加骨量

A novel variant of NOTCH2 causes skeletal fragility

NOTCH2 的一种新型变体导致骨骼脆弱

NOTCH2 disrupts the synovial fibroblast identity and the inflammatory response of epiphyseal chondrocytes

NOTCH2 会破坏滑膜成纤维细胞的特性以及骨骺软骨细胞的炎症反应。

A NOTCH3 pathogenic variant influences osteogenesis and can be targeted by antisense oligonucleotides in induced pluripotent stem cells

NOTCH3致病变异会影响成骨作用，并且可以通过诱导多能干细胞中的反义寡核苷酸进行靶向治疗。

A NOTCH2 pathogenic variant and HES1 regulate osteoclastogenesis in induced pluripotent stem cells

NOTCH2致病变异体和HES1调控诱导多能干细胞中的破骨细胞生成

Role of Metformin in Improving Non-Union Bone Fracture Healing in a Diabetic Rat Model

二甲双胍在改善糖尿病大鼠模型骨不连骨折愈合中的作用

TNFα has differential effects on the transcriptome profile of selected populations in murine cartilage

TNFα对小鼠软骨中特定细胞群的转录组谱具有不同的影响

Induced pluripotent stem cell technology in bone biology

诱导多能干细胞技术在骨生物学中的应用

Antisense oligonucleotides targeting a NOTCH3 mutation in male mice ameliorate the cortical osteopenia of lateral meningocele syndrome

针对雄性小鼠 NOTCH3 突变的反义寡核苷酸可改善侧脑膜膨出综合征的皮质骨减少症。