日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ULK1 drives NDP52-mediated selective autophagic degradation of MHC-I to promote immune evasion in HPV-positive head and neck cancer

ULK1驱动NDP52介导的MHC-I选择性自噬降解,从而促进HPV阳性头颈癌的免疫逃逸。

Vu, Lexi; Giacobbi, Nicholas S; Khalil, Mohamed I; Yang, Canchai; Eckerman, William J; Recinos, Evelyn Gomez; Garber, Johnathon D; Son, Hyomin; Chahal, Prerna; Villa, Dara M; Srivastava, Tasha; Bennett, Abigail Z; Martin, Katie R; Welbon, Craig C; Williamson, Caitlin; Spanos, William C; MacKeigan, Jeffrey P; Olive, Andrew J; Pyeon, Dohun

The membrane-associated ubiquitin ligase MARCHF8 degrades MHC-I in HPV-positive head and neck cancer for immune evasion

膜相关泛素连接酶MARCHF8降解HPV阳性头颈癌中的MHC-I,从而逃避免疫攻击。

Khalil, Mohamed I; Wang, Jie; Vu, Lexi; Yang, Canchai; Yin, Congcong; Chadha, Smriti; Nabors, Harrison; Vocelle, Daniel; May, Danielle G; Chrisopulos, Rachel J; Welbon, Craig C; Zhou, Li; Roux, Kyle J; Spanos, William C; Bernard, Matthew P; Mi, Qing-Sheng; Pyeon, Dohun

Nanoscopic acoustic vibrational dynamics of a single virus captured by ultrafast spectroscopy

利用超快光谱技术捕捉单个病毒的纳米级声学振动动力学

Zhang, Yaqing; Wu, Rihan; Shahjahan, Md; Yang, Canchai; Pyeon, Dohun; Harel, Elad

Inducing Long Lasting B Cell and T Cell Immunity Against Multiple Variants of SARS-CoV-2 Through Mutant Bacteriophage Qβ-Receptor Binding Domain Conjugate

通过突变噬菌体Qβ-受体结合域缀合物诱导针对多种SARS-CoV-2变体的持久B细胞和T细胞免疫

Tan, Zibin; Yang, Canchai; Lin, Po-Han; Ramadan, Sherif; Yang, Weizhun; Rashidi, Zahra; Lang, Shuyao; Shafieichaharberoud, Fatemeh; Gao, Jia; Pan, Xingling; Soloff, Nachy; Wu, Xuanjun; Bolin, Steven; Pyeon, Dohun; Huang, Xuefei

The membrane-associated ubiquitin ligase MARCHF8 stabilizes the human papillomavirus oncoprotein E7 by degrading CUL1 and UBE2L3 in head and neck cancer

膜相关泛素连接酶 MARCHF8 通过降解头颈癌中的 CUL1 和 UBE2L3 来稳定人乳头瘤病毒癌蛋白 E7

Mohamed I Khalil, Canchai Yang, Lexi Vu, Smriti Chadha, Harrison Nabors, Claire D James, Iain M Morgan, Dohun Pyeon

HPV upregulates MARCHF8 ubiquitin ligase and inhibits apoptosis by degrading the death receptors in head and neck cancer

HPV 上调 MARCHF8 泛素连接酶并通过降解头颈癌中的死亡受体来抑制细胞凋亡

Mohamed I Khalil, Canchai Yang, Lexi Vu, Smriti Chadha, Harrison Nabors, Craig Welbon, Claire D James, Iain M Morgan, William C Spanos, Dohun Pyeon

Rational Design and Synthesis of D-galactosyl Lysophospholipids as Selective Substrates and non-ATP-competitive Inhibitors of Phosphatidylinositol Phosphate Kinases

合理设计和合成 D-半乳糖基溶血磷脂作为磷脂酰肌醇磷酸激酶的选择性底物和非 ATP 竞争性抑制剂

Mengxia Sun, Chi Zhang, Dexin Sui, Canchai Yang, Dohun Pyeon, Xuefei Huang, Jian Hu

The membrane-associated ubiquitin ligase MARCHF8 stabilizes the human papillomavirus oncoprotein E7 by degrading CUL1 and UBE2L3 in head and neck cancer

膜相关泛素连接酶 MARCHF8 通过降解头颈癌中的 CUL1 和 UBE2L3 来稳定人乳头瘤病毒癌蛋白 E7

Mohamed I Khalil, Canchai Yang, Lexi Vu, Smriti Chadha, Harrison Nabors, Claire D James, Iain M Morgan, Dohun Pyeon

Na+/H+ Exchanger Regulatory Factor 1 Mediates the Pathogenesis of Airway Inflammation in a Murine Model of House Dust Mite-Induced Asthma

Na+/H+ 交换调节因子 1 介导小鼠尘螨诱发哮喘模型中气道炎症的发病机制

Ananth K Kammala, Devika Bahal, Canchai Yang, Reynold A Panettieri Jr, Rupali Das, Hariharan Subramanian

A Critical Role for Na(+)/H(+) Exchanger Regulatory Factor 1 in Modulating FcεRI-Mediated Mast Cell Activation

Na(+)/H(+)交换调节因子1在调节FcεRI介导的肥大细胞活化中起关键作用

Kammala, Ananth K; Syed, Meesum; Yang, Canchai; Occhiuto, Christopher J; Subramanian, Hariharan