日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
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2026
影响因子:
–

pH-Rate profiles establish that polyketide synthase dehydratase domains utilize a single-base mechanism

pH-速率曲线表明，聚酮合酶脱水酶结构域利用单碱机制。

期刊:Organic & Biomolecular Chemistry
影响因子:2.7
doi:10.1039/c8ob02637h
Xie, Xinqiang; Cane, David E
发表日期：2018
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Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes

表异异戊二烯合酶活性位点口袋中芳香族残基被极性残基取代，导致新的环状倍半萜的生成。

期刊:Biochemistry
影响因子:3
doi:10.1021/acs.biochem.7b00895
Blank, Patrick N; Barrow, Golda H; Chou, Wayne K W; Duan, Lian; Cane, David E; Christianson, David W
发表日期：2017
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Exploring the Influence of Domain Architecture on the Catalytic Function of Diterpene Synthases

探究结构域架构对二萜合成酶催化功能的影响

期刊:Biochemistry
影响因子:3
doi:10.1021/acs.biochem.7b00137
Pemberton, Travis A; Chen, Mengbin; Harris, Golda G; Chou, Wayne K W; Duan, Lian; Köksal, Mustafa; Genshaft, Alex S; Cane, David E; Christianson, David W
发表日期：2017
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A Turnstile Mechanism for the Controlled Growth of Biosynthetic Intermediates on Assembly Line Polyketide Synthases

装配线聚酮合酶上生物合成中间体可控生长的旋转门机制

期刊:ACS Central Science
影响因子:10.4
doi:10.1021/acscentsci.5b00321
Lowry, Brian; Li, Xiuyuan; Robbins, Thomas; Cane, David E; Khosla, Chaitan
发表日期：2016
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Structure and mechanism of assembly line polyketide synthases

装配线聚酮合酶的结构和机制

期刊:Current Opinion in Structural Biology
影响因子:7
doi:10.1016/j.sbi.2016.05.009
Robbins, Thomas; Liu, Yu-Chen; Cane, David E; Khosla, Chaitan
发表日期：2016
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Structure and Function of Fusicoccadiene Synthase, a Hexameric Bifunctional Diterpene Synthase

六聚体双功能二萜合酶——梭菌烯合酶的结构和功能

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.5b00960
Chen, Mengbin; Chou, Wayne K W; Toyomasu, Tomonobu; Cane, David E; Christianson, David W
发表日期：2016
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Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase

探究活性位点水在马兜铃烯合酶催化的倍半萜环化反应中的作用

期刊:Biochemistry
影响因子:3
doi:10.1021/acs.biochem.6b00343
Chen, Mengbin; Chou, Wayne K W; Al-Lami, Naeemah; Faraldos, Juan A; Allemann, Rudolf K; Cane, David E; Christianson, David W
发表日期：2016
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Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with αα Domain Architecture That Catalyzes a Unique Cyclization-Fragmentation Reaction Sequence

土臭素合成酶的结构研究：一种具有αα结构域的双功能倍半萜合成酶，可催化独特的环化-断裂反应序列

期刊:Biochemistry
影响因子:3
doi:10.1021/acs.biochem.5b01143
Harris, Golda G; Lombardi, Patrick M; Pemberton, Travis A; Matsui, Tsutomu; Weiss, Thomas M; Cole, Kathryn E; Köksal, Mustafa; Murphy, Frank V 4th; Vedula, L Sangeetha; Chou, Wayne K W; Cane, David E; Christianson, David W
发表日期：2015
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Engineered Streptomyces avermitilis host for heterologous expression of biosynthetic gene cluster for secondary metabolites

工程改造的链霉菌（Streptomyces avermitilis）宿主用于异源表达次级代谢产物的生物合成基因簇

期刊:ACS Synthetic Biology
影响因子:3.9
doi:10.1021/sb3001003
Komatsu, Mamoru; Komatsu, Kyoko; Koiwai, Hanae; Yamada, Yuuki; Kozone, Ikuko; Izumikawa, Miho; Hashimoto, Junko; Takagi, Motoki; Omura, Satoshi; Shin-ya, Kazuo; Cane, David E; Ikeda, Haruo
代谢
发表日期：2013
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Effect of isotopically sensitive branching on product distribution for pentalenene synthase: support for a mechanism predicted by quantum chemistry

同位素敏感支链对戊烯合酶产物分布的影响：支持量子化学预测的机制

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/ja3043245
Zu, Liansuo; Xu, Meimei; Lodewyk, Michael W; Cane, David E; Peters, Reuben J; Tantillo, Dean J
发表日期：2012
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