文献库，生知库 | 链接生命科学的每一步

Cao, Jiahui; Luo, Ran; Miao, Rourou; Li, Wen; Zhu, Baisong; Yu, Liu; Fu, Yiqiu; Wang, Xinyi; Zhang, Jinxie; Zeng, Wenfeng; Zhang, Hanjie; Mao, Zhuo; Zhang, Fan; Lin, Yao-Xin; Ou, Meitong; Mei, Lin

炎症/感染

囊泡

外泌体

炎症

发表日期：2026

文献求助收藏

Single-cell multi-omics reveals DUSP9 as a key regulator of cancer stemness and a potential therapeutic target in hepatocellular carcinoma

单细胞多组学揭示DUSP9是癌症干细胞特性的关键调控因子，也是肝细胞癌的潜在治疗靶点。

期刊:Journal of Translational Medicine

影响因子:7.5

doi:10.1186/s12967-025-07630-9

Xu, Zhaoyuan; Zhai, Xurun; Liu, Mingxin; Zhang, Yi; Cao, Jiahui; He, Junkai; Li, Haoyi; Liang, Ruopeng; Wang, Weijie; Zhu, Rongtao; Sun, Yuling

The bacteriophage-encoded regulator PemR attenuates Pseudomonas aeruginosa virulence by hijacking quorum sensing and metabolism

噬菌体编码的调节因子PemR通过劫持群体感应和代谢来减弱铜绿假单胞菌的毒力。

期刊:Journal of Virology

影响因子:3.8

doi:10.1128/jvi.02071-25

Yan, Wenbo; Yang, Yingxin; Cao, Jiahui; Zhang, Mengyao; Yang, Yiming; Li, Chao; Zhang, Nan; Yuan, Lixin; Li, Meng; Liu, Lijun; Zhang, Yani; Wang, Shiwei; Wang, Tietao

代谢

发表日期：2026

文献求助收藏

RETINAL PHOTORECEPTORS AND ARTERIOLES ALTERATIONS DETECTED USING ADAPTIVE OPTICS SCANNING LASER OPHTHALMOSCOPY IN DIABETES AND DIABETIC RETINOPATHY

利用自适应光学扫描激光眼底镜检测糖尿病和糖尿病视网膜病变患者的视网膜感光细胞和小动脉改变

期刊:Retina-The Journal of Retinal and Vitreous Diseases

影响因子:2.1

doi:10.1097/IAE.0000000000004647

Su, Ting; Lai, Chunran; Du, Zijing; Cao, Jiahui; Wang, Yaxin; Wang, Shan; Li, Qinyi; Wu, Qiaowei; Hu, Yijun; Fang, Ying; Zhang, Xiayin; Yu, Honghua

Light up the mitochondria: Smart tungstate-oligosaccharide nanoplatform orchestrates mitochondrial transfer from M2 macrophages to restore endothelial function for adaptive diabetic wound regeneration

激活线粒体：智能钨酸盐-寡糖纳米平台调控M2巨噬细胞的线粒体转移，从而恢复内皮功能，促进糖尿病伤口适应性再生。

期刊:Materials Today Bio

影响因子:10.2

doi:10.1016/j.mtbio.2025.102196

Huang, Xiuhong; Lin, Ziling; Ruan, Mingshu; Huang, Peizhen; Ding, Hongmei; Pan, Hao; Cao, Jiahui; Ma, Chunmei; Zhao, Qianhao; Guo, Wenping; Wu, Keke; Fang, Chongkai; Liu, Aijun; Zheng, Liqin

METTL16 suppresses ferroptosis in cholangiocarcinoma by promoting ATF4 via m(6)A modification

METTL16 通过 m(6)A 修饰促进 ATF4 的表达，从而抑制胆管癌细胞中的铁死亡。

期刊:International Journal of Biological Sciences

影响因子:10

doi:10.7150/ijbs.97886

Zhao, Senfeng; Cao, Jiahui; Liang, Ruopeng; Peng, Tingting; Wu, Shitao; Liu, Zhipu; Wu, Yahui; Song, Liming; Sun, Chenguang; Liu, Yin; Gu, Junmou; Wang, Libo; Zhu, Rongtao; Wang, Weijie; Sun, Yuling

High metastatic tumor-derived CXCL16 mediates liver colonization metastasis by inducing Kupffer cell polarization via the PI3K/AKT/FOXO3a pathway.

高转移性肿瘤来源的 CXCL16 通过 PI3K/AKT/FOXO3a 通路诱导 Kupffer 细胞极化，从而介导肝脏定植转移

期刊:Neoplasia

影响因子:7.7

doi:10.1016/j.neo.2025.101174

Liu Yin, Zhai Yunpeng, Zhang Yi, Song Liming, Zhang Hanyue, Cao Jiahui, Zhao Senfeng, Wu Yahui, Liang Ruopeng, Zhu Rongtao, Wang Weijie, Sun Yuling

Silibinin Alleviates Liver Oxidative Stress in D-Galactose-Treated Kunming Mice via Microbiota Homeostasis in a Microbiota-Dependent Manner

水飞蓟宾通过微生物群依赖的方式，利用微生物群稳态缓解D-半乳糖处理的昆明小鼠的肝脏氧化应激

期刊:Antioxidants

影响因子:6.6

doi:10.3390/antiox14091087

Dong, Ao; Zhang, Xianglong; Ma, Jianxiang; Cao, Jiahui; Diene, Gnagna; Xu, Yiou; Yin, Xiujie; Li, Yang; Zhang, Yonggen

ROS-Responsive Nanosystem Targeted Co-Delivery YC-1 and Regorafenib to Alleviate Hypoxia Enhancing Hepatocellular Carcinoma Therapy

利用ROS响应型纳米系统靶向共递送YC-1和瑞戈非尼以缓解缺氧，增强肝细胞癌治疗效果

期刊:International Journal of Nanomedicine

影响因子:6.5

doi:10.2147/IJN.S518120

Song, Liming; Wu, Yahui; Zhao, Senfeng; Liu, Yin; Liu, Zhipu; Zhai, Yunpeng; Cao, Jiahui; Xia, Yaning; Liang, Ruopeng; Wang, Weijie; Zhu, Rongtao; Sun, Binghua; Shi, Yupeng; Sun, Yuling

Optic disc morphometrics as a potential ocular biomarker for depression: evidence from two cross-sectional cohort studies

视盘形态测量学作为抑郁症的潜在眼部生物标志物：来自两项横断面队列研究的证据

期刊:Translational Psychiatry

影响因子:6.2

doi:10.1038/s41398-025-03691-y

Zhang, Xiayin; Wang, Shan; Wang, Yan; Jia, Fujun; Wagner, Siegfried K; Wang, Yujie; Li, Qinyi; Ran, Anran; Li, Cong; Cao, Jiahui; Yang, Yuan; Hu, Yijun; Liu, Lei; Cheung, Carol Y; Keane, Pearse A; Cheng, Ching-Yu; Yang, Xiaohong; Zhu, Zhuoting; Yu, Honghua

Engineered exosome nanovesicles for delivery of antibodies to treat inflammatory bowel disease

工程化外泌体纳米囊泡用于递送抗体以治疗炎症性肠病

Single-cell multi-omics reveals DUSP9 as a key regulator of cancer stemness and a potential therapeutic target in hepatocellular carcinoma

单细胞多组学揭示DUSP9是癌症干细胞特性的关键调控因子，也是肝细胞癌的潜在治疗靶点。

The bacteriophage-encoded regulator PemR attenuates Pseudomonas aeruginosa virulence by hijacking quorum sensing and metabolism

噬菌体编码的调节因子PemR通过劫持群体感应和代谢来减弱铜绿假单胞菌的毒力。

RETINAL PHOTORECEPTORS AND ARTERIOLES ALTERATIONS DETECTED USING ADAPTIVE OPTICS SCANNING LASER OPHTHALMOSCOPY IN DIABETES AND DIABETIC RETINOPATHY

利用自适应光学扫描激光眼底镜检测糖尿病和糖尿病视网膜病变患者的视网膜感光细胞和小动脉改变

Light up the mitochondria: Smart tungstate-oligosaccharide nanoplatform orchestrates mitochondrial transfer from M2 macrophages to restore endothelial function for adaptive diabetic wound regeneration

激活线粒体：智能钨酸盐-寡糖纳米平台调控M2巨噬细胞的线粒体转移，从而恢复内皮功能，促进糖尿病伤口适应性再生。

METTL16 suppresses ferroptosis in cholangiocarcinoma by promoting ATF4 via m(6)A modification

METTL16 通过 m(6)A 修饰促进 ATF4 的表达，从而抑制胆管癌细胞中的铁死亡。

High metastatic tumor-derived CXCL16 mediates liver colonization metastasis by inducing Kupffer cell polarization via the PI3K/AKT/FOXO3a pathway.

高转移性肿瘤来源的 CXCL16 通过 PI3K/AKT/FOXO3a 通路诱导 Kupffer 细胞极化，从而介导肝脏定植转移

Silibinin Alleviates Liver Oxidative Stress in D-Galactose-Treated Kunming Mice via Microbiota Homeostasis in a Microbiota-Dependent Manner

水飞蓟宾通过微生物群依赖的方式，利用微生物群稳态缓解D-半乳糖处理的昆明小鼠的肝脏氧化应激

ROS-Responsive Nanosystem Targeted Co-Delivery YC-1 and Regorafenib to Alleviate Hypoxia Enhancing Hepatocellular Carcinoma Therapy

利用ROS响应型纳米系统靶向共递送YC-1和瑞戈非尼以缓解缺氧，增强肝细胞癌治疗效果

Optic disc morphometrics as a potential ocular biomarker for depression: evidence from two cross-sectional cohort studies

视盘形态测量学作为抑郁症的潜在眼部生物标志物：来自两项横断面队列研究的证据