日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Population Pharmacokinetics to Support Intravenous and Enteral Methadone Dosing in Children

群体药代动力学研究支持儿童静脉和肠内美沙酮给药方案

Watt, Kevin M; Thompson, Elizabeth J; Lam, Lisa; Zimmerman, Kanecia; Hornik, Christoph P; Atz, Andrew M; Fernandez, Allison; Hupp, Susan R; Bhatt-Mehta, Varsha; Benjamin, Daniel K Jr; Anand, Ravinder; Cohen-Wolkowiez, Michael; Gonzalez, Daniel; Smith, P Brian; Capparelli, Edmund V

Model-based assessment of VRC07-523LS dosing in infants through population pharmacokinetic -pharmacodynamic modelling in adults and infants

基于模型的VRC07-523LS在婴儿中的给药评估:通过成人和婴儿的群体药代动力学-药效学模型

Huynh, Dustin; Nikanjam, Mina; Cunningham, Coleen K; McFarland, Elizabeth J; Muresan, Petronella; Perlowski, Charlotte; Yin, Dwight E; Moye, Jack; Spiegel, Hans; Gama, Lucio; Gaudinski, Martin; Capparelli, Edmund V

Population Pharmacokinetics of Bictegravir During Pregnancy and Postpartum: Role of Adherence in Maintaining Therapeutic Exposure

妊娠期和产后比克替拉韦的群体药代动力学:依从性在维持治疗暴露中的作用

Sun, Steven; Nikanjam, Mina; Mirochnick, Mark; Powis, Kathleen M; Eke, Ahizechukwu C; Stek, Alice; Arora, Priyanka; Cressey, Tim R; Brooks, Kristina M; Best, Brookie M; Capparelli, Edmund V; Momper, Jeremiah D

Author Correction: Sustained aviremia despite anti-retroviral therapy non-adherence in male children after in utero HIV transmission

作者更正:男性儿童在子宫内感染 HIV 后,即使未坚持抗逆转录病毒疗法,仍持续存在病毒血症阴性。

Bengu, Nomonde; Cromhout, Gabriela; Adland, Emily; Govender, Katya; Herbert, Nicholas; Lim, Nicholas; Fillis, Rowena; Sprenger, Kenneth; Vieira, Vinicius; Kannie, Samantha; van Lobenstein, Jeroen; Chinniah, Kogielambal; Kapongo, Constant; Bhoola, Roopesh; Krishna, Malini; Mchunu, Noxolo; Pascucci, Giuseppe Rubens; Cotugno, Nicola; Palma, Paolo; Tagarro, Alfredo; Rojo, Pablo; Roider, Julia; Garcia-Guerrero, Maria C; Ochsenbauer, Christina; Groll, Andreas; Reddy, Kavidha; Giaquinto, Carlo; Rossi, Paolo; Hong, Seohyun; Dong, Krista; Ansari, M Azim; Puertas, Maria C; Ndung'u, Thumbi; Capparelli, Edmund; Lichterfeld, Mathias; Martinez-Picado, Javier; Kappes, John C; Archary, Moherndran; Goulder, Philip

Safety and pharmacokinetics of N6LS, a broadly neutralising monoclonal antibody for HIV: a phase 1, open-label, dose-escalation study in healthy adults

N6LS(一种广谱中和HIV的单克隆抗体)的安全性和药代动力学:一项在健康成人中进行的1期开放标签剂量递增研究

Wu, Richard L; Houser, Katherine V; Gaudinski, Martin R; Widge, Alicia T; Awan, Seemal F; Carter, Cristina A; Holman, LaSonji A; Saunders, Jamie; Hendel, Cynthia S; Eshun, Aba; Whalen, William R; Wang, Xiaolin; Arthur, Anita; Cunningham, Jennifer E; Beck, Allison; Casazza, Joseph P; Yamshchikov, Galina V; Rothwell, Ro Shauna; Strom, Larisa; Dittakavi, Tejaswi; Happe, Myra; Hickman, Somia P; Conan-Cibotti, Michelle; Carlton, Kevin; Zhang, Lily; Huang, Yunda; Capparelli, Edmund V; Castro, Mike; Lin, Bob C; O'Connell, Sarah; Flach, Britta S; Bailer, Robert T; Narpala, Sandeep R; Serebryannyy, Leonid; McDermott, Adrian B; Arnold, Frank J; Gall, Jason G; Vazquez, Sandra; Berkowitz, Nina M; Gordon, Ingelise J; Chen, Grace L; Kwong, Peter D; Huang, Jinghe; Pierson, Theodore C; Connors, Mark; Mascola, John R; Zhou, Tongqing; Doria-Rose, Nicole A; Koup, Richard A; Dropulic, Lesia K

ART-free HIV-1 remission in children with in-utero HIV-1 after very early ART (IMPAACT P1115): a multicentre, open-label, phase 1/2 proof-of-concept study

早期接受抗逆转录病毒疗法(ART)后,宫内感染HIV-1的儿童可实现无ART治疗的HIV-1缓解(IMPAACT P1115):一项多中心、开放标签、1/2期概念验证研究

Persaud, Deborah; Coletti, Anne; Nelson, Bryan S; Jao, Jennifer; Capparelli, Edmund V; Costello, Diane; Tierney, Camlin; Kekitiinwa, Adeodata R; Nematadzira, Teacler; Njau, Boniface N; Moye, John; Jean-Philippe, Patrick; Korutaro, Violet; Nalugo, Annet; Mbengeranwa, Tapiwa; Chidemo, Tinashe; Mmbaga, Blandina T; Sakasaka, Philoteus A; Cotton, Mark; Jennings, Cheryl; Hoffmann, Carly; Hovind, Laura; Bryson, Yvonne; Chadwick, Ellen G

Subtherapeutic Meropenem Antibiotic Exposure in Children With Septic Shock Assessed by Noncompartmental Pharmacokinetic Analysis in a Prospective Dataset

通过前瞻性数据集的非房室药代动力学分析评估脓毒症休克患儿亚治疗剂量美罗培南抗生素暴露情况

Bradley, John S; Harvey, Helen; Stout, Dayna; Momper, Jeremiah; Capparelli, Edmund; Avedissian, Sean N; Barbato, Courtney; Mak, Robert H; Jones, Tom P; Jones, Douglas; Le, Jennifer

Variability in Meropenem Distribution and Clearance in Children with Sepsis: Population-Based Pharmacokinetics with Assessment of Renal Biomarkers

脓毒症患儿美罗培南分布和清除率的变异性:基于人群的药代动力学及肾脏生物标志物评估

Le, Jennifer; Huynh, Julie; Vo, Brandon; Mai, Annie; Mak, Robert H; Momper, Jeremiah D; Capparelli, Edmund V; Harvey, Helen; Avedissian, Sean; Bradley, Erin; Sitapati, Amy; Singh, Karandeep; Bradley, John S

Virologic effects of broadly neutralizing antibodies VRC01LS and VRC07-523LS on chronic HIV-1 infection

广谱中和抗体VRC01LS和VRC07-523LS对慢性HIV-1感染的病毒学影响

Happe, Myra; Lynch, Rebecca M; Fichtenbaum, Carl J; Heath, Sonya L; Koletar, Susan L; Landovitz, Raphael J; Presti, Rachel M; Santana-Bagur, Jorge L; Tressler, Randall L; Holman, LaSonji A; Novik, Laura; Roa, Jhoanna C; Rothwell, Ro Shauna; Strom, Larisa; Wang, Jing; Hu, Zonghui; Conan-Cibotti, Michelle; Bhatnagar, Anjali M; Dwyer, Bridget; Ko, Sung Hee; Belinky, Frida; Namboodiri, Aryan M; Pandey, Janardan P; Carroll, Robin; Basappa, Manjula; Serebryannyy, Leonid; Narpala, Sandeep R; Lin, Bob C; McDermott, Adrian B; Boritz, Eli A; Capparelli, Edmund V; Coates, Emily E; Koup, Richard A; Ledgerwood, Julie E; Mascola, John R; Chen, Grace L; Tebas, Pablo

Pharmacokinetics of first-line tuberculosis drugs rifampin, isoniazid, ethambutol, and pyrazinamide during pregnancy and postpartum with and without efavirenz-based antiretroviral treatment: IMPAACT P1026s study

一线抗结核药物利福平、异烟肼、乙胺丁醇和吡嗪酰胺在妊娠和产后接受或不接受依非韦伦类抗逆转录病毒治疗时的药代动力学:IMPAACT P1026s 研究

Van Schalkwyk, Marije; Bekker, Adrie; Decloedt, Eric; Wang, Jiajia; Theron, Gerhard B; Cotton, Mark F; Eke, Ahizechukwu C; Cressey, Tim R; Wabwire, Deo; Shapiro, David E; Bacon, Kira; Knowles, Kevin; George, Kathleen; Browning, Renee; Chakhtoura, Nahida; Rungruengthanakit, Kittipong; Wiesner, Lubbe; Capparelli, Edmund V; Stek, Alice M; Mirochnik, Mark; Best, Brookie M