Cappell Steven D相关文献与解析，生知库 | 链接生命科学的每一步

Saykali Bechara, Tran Andy D, Cornwell James A, Caldwell Matthew A, Sangsari Paniz Rezvan, Morgan Nicole Y, Kruhlak Michael J, Cappell Steven D, Ruiz Sergio

发育与干细胞

发表日期：2025

文献求助收藏

Targeting c-MYC and gain-of-function p53 through inhibition or degradation of the kinase LZK suppresses the growth of HNSCC tumors.

通过抑制或降解激酶 LZK 来靶向 c-MYC 和获得功能的 p53，可以抑制 HNSCC 肿瘤的生长

期刊:Science Signaling

影响因子:6.6

doi:10.1126/scisignal.ado2857

Funk Amy L, Katerji Meghri, Afifi Marwa, Nyswaner Katherine, Woodroofe Carolyn C, Edwards Zoe C, Lindberg Eric, Bergman Knickole L, Gough Nancy R, Rubin Maxine R, KarpiÅska Kamila, Trotter Eleanor W, Dash Sweta, Ries Amy L, James Amy, Robinson Christina M, Difilippantonio Simone, Karim Baktiar O, Chang Ting-Chia, Chen Li, Xu Xin, Doroshow James H, Ahel Ivan, Marusiak Anna A, Swenson Rolf E, Cappell Steven D, Brognard John

Author Correction: Loss of CDK4/6 activity in S/G2 phase leads to cell cycle reversal

作者更正：S/G2期CDK4/6活性丧失会导致细胞周期逆转

期刊:Nature

影响因子:48.5

doi:10.1038/s41586-024-07666-9

Cornwell, James A; Crncec, Adrijana; Afifi, Marwa M; Tang, Kristina; Amin, Ruhul; Cappell, Steven D

Targeting GOF p53 and c-MYC through LZK Inhibition or Degradation Suppresses Head and Neck Tumor Growth.

通过抑制或降解 LZK 靶向 GOF p53 和 c-MYC 可抑制头颈部肿瘤生长

期刊:

影响因子:

doi:10.1101/2024.11.19.623840

Funk Amy L, Katerji Meghri, Afifi Marwa, Nyswaner Katherine, Woodroofe Carolyn C, Edwards Zoe C, Lindberg Eric, Bergman Knickole L, Gough Nancy R, Rubin Maxine R, KarpiÅska Kamila, Trotter Eleanor W, Dash Sweta, Ries Amy L, James Amy, Robinson Christina M, Difilippantonio Simone, Karim Baktiar O, Chang Ting-Chia, Chen Li, Xu Xin, Doroshow James H, Ahel Ivan, Marusiak Anna A, Swenson Rolf E, Cappell Steven D, Brognard John

Loss of CDK4/6 activity in S/G2 phase leads to cell cycle reversal

S/G2期CDK4/6活性丧失会导致细胞周期逆转

期刊:Nature

影响因子:48.5

doi:10.1038/s41586-023-06274-3

Cornwell, James A; Crncec, Adrijana; Afifi, Marwa M; Tang, Kristina; Amin, Ruhul; Cappell, Steven D

Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth factor-mediated differentiation

RGS12作为Ras/Raf/MEK支架在神经生长因子介导的分化中的选择性作用

期刊:EMBO Journal

影响因子:8.3

doi:10.1038/sj.emboj.7601659

Willard, Melinda D; Willard, Francis S; Li, Xiaoyan; Cappell, Steven D; Snider, William D; Siderovski, David P

RGS12

发表日期：2007

文献求助收藏

Lineage-specific CDK activity dynamics characterize early mammalian development.

谱系特异性 CDK 活性动态是哺乳动物早期发育的特征

Targeting c-MYC and gain-of-function p53 through inhibition or degradation of the kinase LZK suppresses the growth of HNSCC tumors.

通过抑制或降解激酶 LZK 来靶向 c-MYC 和获得功能的 p53，可以抑制 HNSCC 肿瘤的生长

Author Correction: Loss of CDK4/6 activity in S/G2 phase leads to cell cycle reversal

作者更正：S/G2期CDK4/6活性丧失会导致细胞周期逆转

Targeting GOF p53 and c-MYC through LZK Inhibition or Degradation Suppresses Head and Neck Tumor Growth.

通过抑制或降解 LZK 靶向 GOF p53 和 c-MYC 可抑制头颈部肿瘤生长

Loss of CDK4/6 activity in S/G2 phase leads to cell cycle reversal

S/G2期CDK4/6活性丧失会导致细胞周期逆转

Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth factor-mediated differentiation

RGS12作为Ras/Raf/MEK支架在神经生长因子介导的分化中的选择性作用