Carnosine protects human microglia against Aβ oligomers through a multimodal mechanism of action: inhibition of oxidative stress, rescue of cellular energy status, and enhancement of phagocytosis
肌肽通过多种作用机制保护人小胶质细胞免受Aβ寡聚体的损伤:抑制氧化应激、恢复细胞能量状态和增强吞噬作用。
期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2026.1768094
Privitera, Anna; Cardaci, Vincenzo; Zupan, Matthew C; Di Pietro, Lucia; Carota, Giuseppe; Sibbitts, Jay; Mangione, Renata; Graziani, Andrea; Buccarello, Lucia; Bellia, Francesco; Di Pietro, Valentina; Lazzarino, Giuseppe; Lunte, Susan M; Hartley, Meredith D; Caraci, Filippo; Tavazzi, Barbara; Maiani, Emiliano; Amorini, Angela M; Lazzarino, Giacomo; Caruso, Giuseppe