日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Digital home-based multimodal prehabilitation of colorectal cancer patients prior to surgery (the dHOPE study): a non-inferiority clinical trial protocol

基于数字化家庭的多模式结直肠癌术前康复(dHOPE研究):一项非劣效性临床试验方案

Kleve, Guro; Santa, Chiara Dalla; Kristiansen, Felicia; Tegnander, Marita; Buch, Victoria; Hagemann, Cecilie Steen; Helgheim, Marianne; Engene, Parasto; Pesonen, Henri; Kleveland, Maiken Kojen; Hverven, Greta Lyster; Nilsen, Tormod Skogstad; Vervaart, Mathyn Adrianus Marinus; Aanesen, Helle; Uglane, Kari Thune; Bjelland, Mona; Zory, Raphaël; Chorin, Frédéric; Cardot-Ruffino, Victoire; Beltran, Eva Ester Molina; Neuzillet, Cindy; Soerensen, Mette; Jylhävä, Juulia; Anzar, Irantzu; Normand, Valentin André; Myrstad, Marius; Klungland, Arne; Nilsen, Hilde Loge; Ougland, Rune

PD-1 Blockade Induces Reactivation of Nonproductive T-Cell Responses Characterized by NF-κB Signaling in Patients with Pancreatic Cancer

PD-1阻断可诱导胰腺癌患者中以NF-κB信号通路为特征的非生产性T细胞反应的重新激活

Lestat R Ali ,Patrick J Lenehan ,Victoire Cardot-Ruffino ,Andressa Dias Costa ,Matthew H G Katz ,Todd W Bauer ,Jonathan A Nowak ,Brian M Wolpin ,Thomas A Abrams ,Anuj Patel ,Thomas E Clancy ,Jiping Wang ,Joseph D Mancias ,Matthew J Reilley ,Chee-Chee H Stucky ,Tanios S Bekaii-Saab ,Rawad Elias ,Nipun Merchant ,Craig L Slingluff Jr ,Osama E Rahma ,Stephanie K Dougan

Blockade of IL1β and PD1 with Combination Chemotherapy Reduces Systemic Myeloid Suppression in Metastatic Pancreatic Cancer with Heterogeneous Effects in the Tumor

IL1β 和 PD1 阻断与联合化疗可降低转移性胰腺癌的全身性髓系抑制,并对肿瘤产生异质性影响

Paul E Oberstein, Andressa Dias Costa #, Emily A Kawaler #, Victoire Cardot-Ruffino #, Osama E Rahma, Nina Beri, Harshabad Singh, Thomas A Abrams, Leah H Biller, James M Cleary, Peter Enzinger, Brandon M Huffman, Nadine J McCleary, Kimberly J Perez, Douglas A Rubinson, Benjamin L Schlechter, Rishi S

Transforming Growth Factor-β Blockade in Pancreatic Cancer Enhances Sensitivity to Combination Chemotherapy

胰腺癌中转化生长因子-β阻断可增强对联合化疗的敏感性

Qiang, Li; Hoffman, Megan T; Ali, Lestat R; Castillo, Jaime I; Kageler, Lauren; Temesgen, Ayantu; Lenehan, Patrick; Wang, S Jennifer; Bello, Elisa; Cardot-Ruffino, Victoire; Uribe, Giselle A; Yang, Annan; Dougan, Michael; Aguirre, Andrew J; Raghavan, Srivatsan; Pelletier, Marc; Cremasco, Viviana; Dougan, Stephanie K

Multicenter randomized controlled trial of neoadjuvant chemoradiotherapy alone or in combination with pembrolizumab in patients with resectable or borderline resectable pancreatic adenocarcinoma

一项多中心随机对照试验,比较新辅助放化疗单独使用或联合帕博利珠单抗治疗可切除或临界可切除胰腺腺癌患者的疗效

Katz, Matthew H G; Petroni, Gina R; Bauer, Todd; Reilley, Matthew J; Wolpin, Brian M; Stucky, Chee-Chee; Bekaii-Saab, Tanios S; Elias, Rawad; Merchant, Nipun; Dias Costa, Andressa; Lenehan, Patrick; Cardot-Ruffino, Victoire; Rodig, Scott; Pfaff, Kathleen; Dougan, Stephanie K; Nowak, Jonathan Andrew; Varadhachary, Gauri R; Slingluff, Craig L; Rahma, Osama

G-CSF rescue of FOLFIRINOX-induced neutropenia leads to systemic immune suppression in mice and humans

G-CSF 挽救 FOLFIRINOX 诱导的中性粒细胞减少症会导致小鼠和人类的全身免疫抑制。

Victoire Cardot-Ruffino ,Naima Bollenrucher ,Luisa Delius ,S Jennifer Wang ,Lauren K Brais ,Joshua Remland ,C Elizabeth Keheler ,Keri M Sullivan ,Thomas A Abrams ,Leah H Biller ,Peter C Enzinger ,Nadine J McCleary ,Anuj K Patel ,Douglas A Rubinson ,Benjamin Schlechter ,Sarah Slater ,Matthew B Yurgelun ,James M Cleary ,Kimberly Perez ,Michael Dougan ,Kimmie Ng ,Brian M Wolpin ,Harshabad Singh # ,Stephanie K Dougan #

Hypothalamic-pituitary-adrenal axis activation and glucocorticoid-responsive gene expression in skeletal muscle and liver of Apc mice

Apc 小鼠骨骼肌和肝脏中下丘脑-垂体-肾上腺轴激活和糖皮质激素反应基因表达

Agnès Martin, Josiane Castells, Valentine Allibert, Andréa Emerit, Cindy Zolotoff, Victoire Cardot-Ruffino, Yann S Gallot, Barbara Vernus, Véronique Chauvet, Laurent Bartholin, Laurent Schaeffer, Anne-Cécile Durieux, Christophe Hourdé, François B Favier, Laetitia Mazelin, Damien Freyssenet

SMAD2/3 mediate oncogenic effects of TGF-β in the absence of SMAD4

在没有 SMAD4 的情况下,SMAD2/3 介导 TGF-β 的致癌作用

Adrien Bertrand-Chapel #, Cassandre Caligaris #, Tanguy Fenouil #, Clara Savary #, Sophie Aires #, Sylvie Martel #, Paul Huchedé, Christelle Chassot, Véronique Chauvet, Victoire Cardot-Ruffino, Anne-Pierre Morel, Fabien Subtil, Kayvan Mohkam, Jean-Yves Mabrut, Laurie Tonon, Alain Viari, Philippe Cas

Physical Activity as the Best Supportive Care in Cancer: The Clinician's and the Researcher's Perspectives

体育锻炼作为癌症最佳辅助治疗手段:临床医生和研究人员的视角

Torregrosa, Cécile; Chorin, Frédéric; Beltran, Eva Ester Molina; Neuzillet, Cindy; Cardot-Ruffino, Victoire

Correction: Schwann cells support oncogenic potential of pancreatic cancer cells through TGFβ signaling

更正:雪旺氏细胞通过TGFβ信号通路支持胰腺癌细胞的致癌潜能。

Roger, Elodie; Martel, Sylvie; Bertrand-Chapel, Adrien; Depollier, Arnaud; Chuvin, Nicolas; Pommier, Roxane M; Yacoub, Karam; Caligaris, Cassandre; Cardot-Ruffino, Victoire; Chauvet, Véronique; Aires, Sophie; Mohkam, Kayvan; Mabrut, Jean-Yves; Adham, Mustapha; Fenouil, Tanguy; Hervieu, Valérie; Broutier, Laura; Castets, Marie; Neuzillet, Cindy; Cassier, Philippe A; Tomasini, Richard; Sentis, Stéphanie; Bartholin, Laurent