日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Tissue Virus Microenvironment with Activated Stress Responses Underlies Durable SIV Persistence

组织病毒微环境激活应激反应是SIV持久存在的基础

Hope, Thomas J; Crentsil, Eliana U; Arif, Muhammad S; Thomas, Yanique; Zhang, Ellen; Thuruthiyil, Christopher T; Moriarty, Ryan V; Engelmann, Flora; Pascoe, Sean C; Hasson, Jenna M; Borrowman, Seth H; Shaaban, Maryam A; Allen, Edward J; Monette, Anne; Carias, Ann M; Ferrell, Douglas; Ouguirti, Nawal; Clerc, Isabelle; Hultquist, Judd F; D'Aquila, Richard T; McRaven, Michael D; Araínga, Mariluz; Villinger, Francois; Lorenzo-Redondo, Ramon

Blockade of de novo dNTP biosynthesis pathway delays HIV-1 early life cycle kinetics and dynamics.

阻断从头 dNTP 生物合成途径会延缓 HIV-1 早期生命周期的动力学和动态变化

Siddique Mohammad Anwar, McRaven Michael D, Arif Muhammad Shoaib, Allen Edward J, McKee Charia, Honne Shravya, Sultana Tahmina, Kim Baek, Carias Ann M, Mamede João I, Hope Thomas J

Vaginal microbiome dysbiosis and sexually transmitted infections correlate with concentrations of immunoglobulin isotypes in human cervicovaginal mucus: insights into HIV-1 transmission

阴道微生物群失调和性传播感染与人类宫颈阴道粘液中免疫球蛋白同种型的浓度相关:对 HIV-1 传播的启示

Akiso, Matrona M; Abook, Israel; Mureithi, Marianne W; Kombo, Janet; Koi, Print; Musando, Joel; Chirchir, Ruth J; McRaven, Michael D; Carias, Ann M; Joseph, Sarah; Anzala, Omu; Hope, Thomas J

Endocervix exhibits greater susceptibility to HIV-1 infection compared to ectocervix following ex vivo exposure to Transmitted/Founder HIV-1 variants

与宫颈外口相比,宫颈内口在体外暴露于传播/创始HIV-1变异株后,更容易感染HIV-1。

Langat, Robert; McRaven, Michael D; Lorenzo-Redondo, Ramon; Muhomah, Teresia; Carias, Ann M; Arif, Muhammad Shoaib; Akiso, Matrona Mbendo; Mureithi, Marianne; Anzala, Omu; Gilmour, Jill; Joseph, Sarah; Hope, Thomas J

Transcytosis as a Mechanism of HIV-1 Entry into Columnar Epithelial Explants of the Female Reproductive Tract

胞吞作用是HIV-1进入女性生殖道柱状上皮细胞外植体的机制

Carias, Ann M; Anderson, Meegan; McRaven, Michael; Allen, Edward; Fought, Angela J; Hope, Thomas J

PET/CT Targeted Tissue Sampling Reveals Intravenously Administered HGN194 IgG1 Affects HIV Distribution after Rectal Exposure

PET/CT靶向组织取样显示,静脉注射HGN194 IgG1会影响直肠暴露后HIV的分布

Taylor, Roslyn A; Xiao, Sixia; Carias, Ann M; McRaven, Michael D; Thakkar, Divya N; Araínga, Mariluz; Lorenzo-Redondo, Ramon; Allen, Edward J; Rogers, Kenneth A; Kumarapperuma, Sidath C; Gong, Siqi; Anderson, Meegan R; Thomas, Yanique; Madden, Patrick J; Corti, Davide; Cameroni, Elisabetta; Lanzavecchia, Antonio; Goins, Beth; Fox, Peter; Villinger, Francois J; Ruprecht, Ruth M; Hope, Thomas J

Quantitative Immunofluorescent Imaging of Immune Cells in Mucosal Tissues

黏膜组织中免疫细胞的定量免疫荧光成像

Buchanan, Lane B; Shao, Zhongtian; Jiang, Yuan Chung; Lai, Abbie; Hope, Thomas J; Carias, Ann M; Prodger, Jessica L

PET/CT targeted tissue sampling reveals virus specific dIgA can alter the distribution and localization of HIV after rectal exposure

PET/CT靶向组织取样显示,病毒特异性dIgA可改变直肠暴露后HIV的分布和定位。

Taylor, Roslyn A; Xiao, Sixia; Carias, Ann M; McRaven, Michael D; Thakkar, Divya N; Araínga, Mariluz; Allen, Edward J; Rogers, Kenneth A; Kumarapperuma, Sidath C; Gong, Siqi; Fought, Angela J; Anderson, Meegan R; Thomas, Yanique; Schneider, Jeffrey R; Goins, Beth; Fox, Peter; Villinger, Francois J; Ruprecht, Ruth M; Hope, Thomas J

Localization of infection in neonatal rhesus macaques after oral viral challenge

新生恒河猴口服病毒攻击后感染部位的定位

Taylor, Roslyn A; McRaven, Michael D; Carias, Ann M; Anderson, Meegan R; Matias, Edgar; Araínga, Mariluz; Allen, Edward J; Rogers, Kenneth A; Gupta, Sandeep; Kulkarni, Viraj; Lakhashe, Samir; Lorenzo-Redondo, Ramon; Thomas, Yanique; Strickland, Amanda; Villinger, Francois J; Ruprecht, Ruth M; Hope, Thomas J

Deep Gene Sequence Cluster Analyses of Multi-Virus-Infected Mucosal Tissue Reveal Enhanced Transmission of Acute HIV-1

对多种病毒感染的黏膜组织进行深度基因序列聚类分析,揭示急性 HIV-1 传播增强。

Klein, Katja; Nankya, Immaculate; Nickel, Gabrielle; Ratcliff, Annette N; Meadows, Adam A J; Hathaway, Nicholas; Bailey, Jeffrey A; Stieh, Daniel J; Cheeseman, Hannah M; Carias, Ann M; Lobritz, Michael A; Mann, Jamie F S; Gao, Yong; Hope, Thomas J; Shattock, Robin J; Arts, Eric J