日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

First-in-human, double-blind, randomized phase 1b study of peptide immunotherapy IMCY-0098 in new-onset type 1 diabetes: an exploratory analysis of immune biomarkers

首次人体双盲随机 1b 期研究:肽免疫疗法 IMCY-0098 治疗新发 1 型糖尿病:免疫生物标志物的探索性分析

Van Rampelbergh, Jean; Achenbach, Peter; Leslie, Richard David; Kindermans, Martin; Parmentier, Frédéric; Carlier, Vincent; Bovy, Nicolas; Vanderelst, Luc; Van Mechelen, Marcelle; Vandepapelière, Pierre; Boitard, Christian

First-in-human, double-blind, randomized phase 1b study of peptide immunotherapy IMCY-0098 in new-onset type 1 diabetes

首次人体双盲随机1b期研究,评估肽免疫疗法IMCY-0098治疗新发1型糖尿病的疗效

Van Rampelbergh, Jean; Achenbach, Peter; Leslie, Richard David; Ali, Mohammad Alhadj; Dayan, Colin; Keymeulen, Bart; Owen, Katharine R; Kindermans, Martin; Parmentier, Frédéric; Carlier, Vincent; Ahangarani, Roxana R; Gebruers, Evelien; Bovy, Nicolas; Vanderelst, Luc; Van Mechelen, Marcelle; Vandepapelière, Pierre; Boitard, Christian

MHC Class II-Restricted Epitopes Containing an Oxidoreductase Activity Prompt CD4(+) T Cells with Apoptosis-Inducing Properties

含有氧化还原酶活性的MHC II类限制性表位可诱导CD4(+) T细胞产生凋亡诱导特性。

Malek Abrahimians, Elin; Carlier, Vincent A; Vander Elst, Luc; Saint-Remy, Jean-Marie R

Increased synapse formation obtained by T cell epitopes containing a CxxC motif in flanking residues convert CD4+ T cells into cytolytic effectors

含有侧翼残基 CxxC 基序的 T 细胞表位可促进突触形成,从而将 CD4+ T 细胞转化为细胞毒性效应细胞。

Carlier, Vincent A; VanderElst, Luc; Janssens, Wim; Jacquemin, Marc G; Saint-Remy, Jean-Marie R

Retroviral vectors induce epigenetic chromatin modifications and IL-10 production in transduced B cells via activation of toll-like receptor 2.

逆转录病毒载体通过激活 Toll 样受体 2,诱导转导 B 细胞的表观遗传染色质修饰和 IL-10 产生

Ahangarani Roxana R, Janssens Wim, Carlier Vincent, Vanderelst Luc, Vandendriessche Thierry, Chuah Marinee, Jacquemin Marc, Saint-Remy Jean-Marie