日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Scaling up spatial transcriptomics for large-sized tissues: uncovering cellular-level tissue architecture beyond conventional platforms with iSCALE

利用 iSCALE 将空间转录组学扩展到大尺寸组织:揭示超越传统平台的细胞级组织结构

Schroeder, Amelia; Loth, Melanie L; Luo, Chunyu; Yao, Sicong; Yan, Hanying; Zhang, Daiwei; Piya, Sarbottam; Plowey, Edward; Hu, Wenxing; Clemenceau, Jean R; Jang, Inyeop; Kim, Minji; Barnfather, Isabel; Chan, Su Jing; Reynolds, Taylor L; Carlile, Thomas; Cullen, Patrick; Sung, Ji-Youn; Tsai, Hui-Hsin; Park, Jeong Hwan; Hwang, Tae Hyun; Zhang, Baohong; Li, Mingyao

Dorsal root ganglion toxicity after AAV intra-CSF delivery of a RNAi expression construct into non-human primates and mice.

将 RNAi 表达构建体通过 AAV 脑脊液内递送至非人灵长类动物和小鼠后,引起背根神经节毒性

Hawley Zachary C E, Pardo Ingrid D, Cao Shaolong, Zavodszky Maria I, Casey Fergal, Ferber Kyle, Luo Yi, Hana Sam, Chen Shukkwan K, Doherty Jessica, Costa Raquel, Cullen Patrick, Liu Yuqing, Carlile Thomas M, Chowdhury Twinkle, Doyle Benjamin, Clarner Pete, Mangaudis Kevin, Guilmette Edward, Bourque Shawn, Koske David, Nadella Murali V P, Trapa Patrick, Hawes Michael L, Raitcheva Denitza, Lo Shih-Ching

Viral-mediated knockdown of Atxn2 attenuates TDP-43 pathology and muscle dysfunction in the PFN1(C71G) ALS mouse model.

病毒介导的 Atxn2 敲低可减轻 PFN1(C71G) ALS 小鼠模型中的 TDP-43 病理和肌肉功能障碍

Hawley Zachary C E, Li Xueying, Bodnar Dora, Gu Yuanzheng, Luo Yi, Ferretti Daniel, Sheehy Adam, Driscoll Rachelle, Zavodszky Maria I, Cao Shaolong, Isaza Isabel, Jandreski Luke, Liu Yuqing, Carlile Thomas, Lo Shih-Ching, Grimard Anna, Bourque Shawn, Utturkar Aditya, Desmarais Samantha, Arnold H Moore, Huh Dann, Guilmette Edward, Kwon Deborah Y

Inhibition of immune response reduces pathology in dorsal root ganglia and peripheral nerves in cynomolgus macaques following AAV gene therapy

抑制免疫反应可减轻食蟹猴在接受腺相关病毒(AAV)基因治疗后背根神经节和周围神经的病理变化。

Grubor, Branka; Henry, Kate L; Chan, Su Jing; Sheehan, Mark; Shah, Anumeha; Pellerin, Alex; Bai, Judy; Nadella, Prasad; Bommegowda, Santhosh; Cullen, Patrick; Tien, Eric; Chen, Vivian; van der Munnik, Nicholas P; White-Hunt, Stephanie; Plowey, Edward D; Hamann, Stefan; Guise, Amanda J; Xu, Shanqin; Kirkland, Melissa; Doherty, Jessica; Lyashenko, Eugenia; Bhat, Guruharsha; Glajch, Kelly; Lo, Shih-Ching; Gianni, Davide; Clarner, Pete; Gagnon, Jake; Chu, Jenhwa; Nambiar, Kalyani; Lulla, Mukesh; Zheng, Fengmei; Weldeab, Asmerom; Bartlett, Dan; Gutnick, Amos; Reynolds, Taylor; Zhu, Kan; Huh, Dann; Carlile, Thomas M; Fikes, James; Trapa, Patrick; Suh, Junghae; Morris, Dale; Burkly, Linda

Scaling up spatial transcriptomics for large-sized tissues: uncovering cellular-level tissue architecture beyond conventional platforms with iSCALE.

利用 iSCALE 将空间转录组学扩展到大组织:揭示超越传统平台的细胞级组织结构

Schroeder Amelia, Loth Melanie, Luo Chunyu, Yao Sicong, Yan Hanying, Zhang Daiwei, Piya Sarbottam, Plowey Edward, Hu Wenxing, Clemenceau Jean R, Jang Inyeop, Kim Minji, Barnfather Isabel, Chan Su Jing, Reynolds Taylor L, Carlile Thomas, Cullen Patrick, Sung Ji-Youn, Tsai Hui-Hsin, Park Jeong Hwan, Hwang Tae Hyun, Zhang Baohong, Li Mingyao

Aneuploid yeast strains exhibit defects in cell growth and passage through START

非整倍体酵母菌株在细胞生长和通过START细胞传代过程中表现出缺陷。

Thorburn, Rebecca R; Gonzalez, Christian; Brar, Gloria A; Christen, Stefan; Carlile, Thomas M; Ingolia, Nicholas T; Sauer, Uwe; Weissman, Jonathan S; Amon, Angelika

Genomes and characterization of phages Bcep22 and BcepIL02, founders of a novel phage type in Burkholderia cenocepacia

伯克霍尔德氏菌中一种新型噬菌体类型的创始噬菌体Bcep22和BcepIL02的基因组和特征分析

Gill, Jason J; Summer, Elizabeth J; Russell, William K; Cologna, Stephanie M; Carlile, Thomas M; Fuller, Alicia C; Kitsopoulos, Kate; Mebane, Leslie M; Parkinson, Brandi N; Sullivan, David; Carmody, Lisa A; Gonzalez, Carlos F; LiPuma, John J; Young, Ry

Divergence and mosaicism among virulent soil phages of the Burkholderia cepacia complex

伯克霍尔德氏菌属洋葱伯克霍尔德菌复合群毒性土壤噬菌体的分化和嵌合现象

Summer, Elizabeth J; Gonzalez, Carlos F; Bomer, Morgan; Carlile, Thomas; Embry, Addie; Kucherka, Amalie M; Lee, Jonte; Mebane, Leslie; Morrison, William C; Mark, Louise; King, Maria D; LiPuma, John J; Vidaver, Anne K; Young, Ry