日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An Inhibitor of Death-Associated Protein Kinase 3 (DAPK3) Disrupts Hippo Signaling and Intestinal Epithelial Regeneration in Murine DSS-Induced Colitis

死亡相关蛋白激酶3 (DAPK3) 抑制剂可破坏小鼠DSS诱导的结肠炎中的Hippo信号通路和肠上皮再生

Chen, Huey-Miin; Carlson, David A; Haystead, Timothy A J; MacDonald, Justin A

Homodimeric Granzyme A Opsonizes Mycobacterium tuberculosis and Inhibits Its Intracellular Growth in Human Monocytes via Toll-Like Receptor 4 and CD14

同型二聚体颗粒酶 A 通过 Toll 样受体 4 和 CD14 调理结核分枝杆菌并抑制其在人类单核细胞中的细胞内生长

Valerio Rasi, Kathleen R Phelps, Keegan R Paulson, Christopher S Eickhoff, Mathivanan Chinnaraj, Nicola Pozzi, Marco Di Gioia, Ivan Zanoni, Shubha Shakya, Haley L Carlson, David A Ford, Grant R Kolar, Daniel F Hoft

Cooperative involvement of zipper-interacting protein kinase (ZIPK) and the dual-specificity cell-division cycle 14A phosphatase (CDC14A) in vascular smooth muscle cell migration

拉链相互作用蛋白激酶 (ZIPK) 和双特异性细胞分裂周期 14A 磷酸酶 (CDC14A) 在血管平滑肌细胞迁移中的协同作用

Al-Ghabkari, Abdulhameed; Carlson, David A; Haystead, Timothy A J; MacDonald, Justin A

A symbiotic physical niche in Drosophila melanogaster regulates stable association of a multi-species gut microbiota

果蝇的共生物理生态位调节多物种肠道微生物群的稳定关联

Ren Dodge, Eric W Jones, Haolong Zhu, Benjamin Obadia, Daniel J Martinez, Chenhui Wang, Andrés Aranda-Díaz, Kevin Aumiller, Zhexian Liu, Marco Voltolini, Eoin L Brodie, Kerwyn Casey Huang, Jean M Carlson, David A Sivak, Allan C Spradling, William B Ludington3

A highly selective inhibitor of interleukin-1 receptor-associated kinases 1/4 (IRAK-1/4) delineates the distinct signaling roles of IRAK-1/4 and the TAK1 kinase.

白细胞介素-1受体相关激酶1/4(IRAK-1/4)的高选择性抑制剂阐明了IRAK-1/4和TAK1激酶不同的信号传导作用

Scarneo Scott A, Hughes Philip F, Yang Kelly W, Carlson David A, Gurbani Deepak, Westover Kenneth D, Haystead Timothy A J

Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2(+) Breast Cancer

Fasnall是一种选择性FASN抑制剂,在HER2(+)乳腺癌的MMTV-Neu模型中显示出强大的抗肿瘤活性。

Alwarawrah, Yazan; Hughes, Philip; Loiselle, David; Carlson, David A; Darr, David B; Jordan, Jamie L; Xiong, Jessie; Hunter, Lucas M; Dubois, Laura G; Thompson, J Will; Kulkarni, Manjusha M; Ratcliff, Annette N; Kwiek, Jesse J; Haystead, Timothy A J

Phenotypic Characterization of Toxic Compound Effects on Liver Spheroids Derived from iPSC Using Confocal Imaging and Three-Dimensional Image Analysis

使用共聚焦成像和三维图像分析对来自 iPSC 的肝球体毒性化合物影响的表型表征

Oksana Sirenko, Michael K Hancock, Jayne Hesley, Dihui Hong, Avrum Cohen, Jason Gentry, Coby B Carlson, David A Mann

Identification of an allosteric small-molecule inhibitor selective for the inducible form of heat shock protein 70

鉴定出一种对诱导型热休克蛋白70具有选择性的变构小分子抑制剂

Howe, Matthew K; Bodoor, Khaldon; Carlson, David A; Hughes, Philip F; Alwarawrah, Yazan; Loiselle, David R; Jaeger, Alex M; Darr, David B; Jordan, Jamie L; Hunter, Lucas M; Molzberger, Eileen T; Gobillot, Theodore A; Thiele, Dennis J; Brodsky, Jeffrey L; Spector, Neil L; Haystead, Timothy A J