日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Challenges and advances for huntingtin detection in cerebrospinal fluid: in support of relative quantification.

脑脊液中亨廷顿蛋白检测的挑战与进展：支持相对定量

期刊:Biomarker Research
影响因子:11.5
doi:10.1186/s40364-025-00772-4
Harding Rachel J, Xie Yuanyun, Caron Nicholas S, Findlay-Black Hailey, Lyu Caroline, Potluri Nalini, Chandrasekaran Renu, Hayden Michael R, Leavitt Blair R, Langbehn Douglas R, Southwell Amber L
其它
发表日期：2025
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Molecular and imaging biomarker responses to brain mutant HTT lowering in a mouse model of Huntington disease.

亨廷顿病小鼠模型中脑突变 HTT 降低的分子和影像生物标志物反应。

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.1
doi:10.1016/j.omtn.2025.102710
Caron Nicholas S, Fan Jianjia, Ma Da, Yung Andrew, Ko Seunghyun, Bale Kirsten, Anderson Christine, Kozlowski Piotr, Pouladi Mahmoud A, Wellington Cheryl L, Hayden Michael R
Mouse
发表日期：2025
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CAG-targeted brain-permeable therapy tested in biallelic humanized polyQ mouse models.

在双等位基因人源化polyQ小鼠模型中测试了CAG靶向脑渗透性疗法

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.1
doi:10.1016/j.omtn.2025.102496
Surdyka Magdalena, Kalinowska-Pośka Żaneta, Niewiadomska-Cimicka Anna, Jesion Ewelina, Fiszer Agnieszka, Singer-Mikosch Elisabeth, Fievet Lorraine, Przybyl Lukasz, Caron Nicholas S, Hayden Michael R, Nguyen Huu Phuc, Trottier Yvon, Figiel Maciej
其它
Human
Mouse
发表日期：2025
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Huntingtin Haplotypes Provide Prioritized Target Panels for Allele-specific Silencing in Huntington Disease Patients of European Ancestry

亨廷顿单倍型为欧洲血统亨廷顿病患者的等位基因特异性沉默提供了优先靶向面板

期刊:Molecular Therapy
影响因子:12
doi:10.1038/mt.2015.128
Kay, Chris; Collins, Jennifer A; Skotte, Niels H; Southwell, Amber L; Warby, Simon C; Caron, Nicholas S; Doty, Crystal N; Nguyen, Betty; Griguoli, Annamaria; Ross, Colin J; Squitieri, Ferdinando; Hayden, Michael R
发表日期：2015
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