Prolonged metformin treatment leads to reduced transcription of Nrf2 and neurotrophic factors without cognitive impairment in older C57BL/6J mice.
长期服用二甲双胍会导致老年 C57BL/6J 小鼠体内 Nrf2 和神经营养因子的转录减少，但不会引起认知障碍
期刊:Behavioural Brain Research
影响因子:2.3
doi:10.1016/j.bbr.2015.12.012
Allard Joanne S, Perez Evelyn J, Fukui Koji, Carpenter Priscilla, Ingram Donald K, de Cabo Rafael
