日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Modulation of IL-17 backbone dynamics reduces receptor affinity and reveals a new inhibitory mechanism.

IL-17骨架动力学的调节降低了受体亲和力,揭示了一种新的抑制机制

Shaw Daniel J, Waters Lorna C, Strong Sarah L, Schulze Monika-Sarah E D, Greetham Gregory M, Towrie Mike, Parker Anthony W, Prosser Christine E, Henry Alistair J, Lawson Alastair D G, Carr Mark D, Taylor Richard J, Hunt Neil T, Muskett Frederick W

Identification, binding, and structural characterization of single domain anti-PD-L1 antibodies inhibitory of immune regulatory proteins PD-1 and CD80

鉴定、结合和结构表征抑制免疫调节蛋白PD-1和CD80的单域抗PD-L1抗体

Kang-Pettinger, Tara; Walker, Kayleigh; Brown, Richard; Cowan, Richard; Wright, Helena; Baravalle, Roberta; Waters, Lorna C; Muskett, Frederick W; Bowler, Matthew W; Sawmynaden, Kovilen; Coombs, Peter J; Carr, Mark D; Hall, Gareth

Sequence-specific (1)H, (13)C and (15)N backbone NMR assignments for the N-terminal IgV-like domain (D1) and full extracellular region (D1D2) of PD-L1

PD-L1 的 N 端 IgV 样结构域 (D1) 和完整胞外区 (D1D2) 的序列特异性 (1)H、(13)C 和 (15)N 骨架 NMR 归属

Walker, Kayleigh; Waters, Lorna C; Kelly, Geoff; Muskett, Frederick W; Carr, Mark D

Structural and functional analysis of Dickkopf 4 (Dkk4): New insights into Dkk evolution and regulation of Wnt signaling by Dkk and Kremen proteins.

Dickkopf 4 (Dkk4) 的结构和功能分析:对 Dkk 进化以及 Dkk 和 Kremen 蛋白对 Wnt 信号传导的调控有了新的认识

Patel Saleha, Barkell Alice M, Gupta Deepti, Strong Sarah L, Bruton Shaun, Muskett Frederick W, Addis Philip W, Renshaw Philip S, Slocombe Patrick M, Doyle Carl, Clargo Alison, Taylor Richard J, Prosser Christine E, Henry Alistair J, Robinson Martyn K, Waters Lorna C, Holdsworth Gill, Carr Mark D

Resonance assignment and secondary structure of the middle MA-3 domain and complete tandem MA-3 region of the tumour suppressor protein Pdcd4

肿瘤抑制蛋白 Pdcd4 的中间 MA-3 结构域和完整串联 MA-3 区域的共振分配和二级结构

Waters, Lorna C; Oka, Ojore; Muskett, Frederick W; Strong, Sarah L; Schmedt, Thore; Klempnauer, Karl-Heinz; Carr, Mark D

Characterization of the structural features and interactions of sclerostin: molecular insight into a key regulator of Wnt-mediated bone formation.

硬骨蛋白的结构特征和相互作用的表征:对 Wnt 介导的骨形成的关键调节因子的分子见解

Veverka Vaclav, Henry Alistair J, Slocombe Patrick M, Ventom Andrew, Mulloy Barbara, Muskett Frederick W, Muzylak Mariusz, Greenslade Kevin, Moore Adrian, Zhang Li, Gong Jianhua, Qian Xueming, Paszty Chris, Taylor Richard J, Robinson Martyn K, Carr Mark D

Structure and function of the complex formed by the tuberculosis virulence factors CFP-10 and ESAT-6

结核病毒力因子CFP-10和ESAT-6形成的复合物的结构和功能

Renshaw, Philip S; Lightbody, Kirsty L; Veverka, Vaclav; Muskett, Fred W; Kelly, Geoff; Frenkiel, Thomas A; Gordon, Stephen V; Hewinson, R Glyn; Burke, Bernard; Norman, Jim; Williamson, Richard A; Carr, Mark D