Carrasco Nancy相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Overnutrition in mice impairs thyroid hormone biosynthesis and utilization, causing hypothyroidism, despite remarkable thyroidal adaptations

小鼠营养过剩会损害甲状腺激素的生物合成和利用，导致甲状腺功能减退，尽管甲状腺有显著的适应性变化。

期刊:Journal of Clinical Investigation

影响因子:13.6

doi:10.1172/JCI194207

Rampy, Jessica; Torres-Manzo, Alejandra Paola; Hoffsmith, Kendra; Loberg, Matthew A; Sheng, Quanhu; Salas-Lucia, Federico; Bianco, Antonio C; Arrojo E Drigo, Rafael; Wang, Huiying; Weiss, Vivian L; Carrasco, Nancy

甲状腺功能减退

免疫/内分泌

发表日期：2026

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Engineering substrate selectivity in the human sodium/iodide symporter (NIS)

改造人类钠/碘同向转运蛋白（NIS）的底物选择性

doi:10.1101/2025.10.07.681042

Llorente-Esteban, Alejandro; Sabbineni, Haswitha; Hoffsmith, Kendra; Manville, Rían W; López-González, David; Reyna-Neyra, Andrea; Leyva, J Alfonso; Abbott, Geoffrey W; Bianchet, Mario A; Carrasco, Nancy

发表日期：2025

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Overnutrition directly impairs thyroid hormone biosynthesis and utilization, causing hypothyroidism, despite remarkable thyroidal adaptations

营养过剩会直接损害甲状腺激素的生物合成和利用，导致甲状腺功能减退，尽管甲状腺具有显著的适应能力。

doi:10.1101/2025.03.31.645596

Rampy, Jessica; Torres-Manzo, Alejandra Paola; Hoffsmith, Kendra; Loberg, Matthew A; Sheng, Quanhu; Salas-Lucia, Federico; Bianco, Antonio C; Arrojo E Drigo, Rafael; Wang, Huiying; Weiss, Vivian L; Carrasco, Nancy

免疫/内分泌

甲状腺功能减退

发表日期：2025

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7350 Association between thyroid function and insulin resistance indices in Korean adolescents: Findings from the 2014-2015 KNHANES

7350 韩国青少年甲状腺功能与胰岛素抵抗指标之间的关联：2014-2015年韩国国民健康与营养调查（KNHANES）的结果

期刊:Nature Medicine

影响因子:50

doi:10.1038/nm.2029

Roepke, Torsten K; King, Elizabeth C; Reyna-Neyra, Andrea; Paroder, Monika; Purtell, Kerry; Koba, Wade; Fine, Eugene; Lerner, Daniel J; Carrasco, Nancy; Abbott, Geoffrey W; Roque, Precious Vanessa; Lopez, Mark Joseph; Sanchez, Tracy Joy; Albano, Marwen Faye; Aquino, Paula Nichaelle; Lo, Anna Melissa; Mun, Eunji; Lee, Hye Ah; Choi, Jung Eun; Lee, Rosie; Kim, Kyung Hee; Kim, Hae Soon

免疫/内分泌

发表日期：2024

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The Iodide Transport Defect-Causing Y348D Mutation in the Na(+)/I(-) Symporter Renders the Protein Intrinsically Inactive and Impairs Its Targeting to the Plasma Membrane

导致碘离子转运缺陷的Na(+)/I(-)同向转运蛋白中的Y348D突变使该蛋白本身失去活性，并损害其向质膜的定位。

影响因子:6.7

doi:10.1089/thy.2020.0931

Reyna-Neyra, Andrea; Jung, Lara; Chakrabarti, Mayukh; Suárez, Mikel X; Amzel, L Mario; Carrasco, Nancy

发表日期：2021

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Allosteric regulation of mammalian Na(+)/I(-) symporter activity by perchlorate

高氯酸盐对哺乳动物Na(+)/I(-)同向转运蛋白活性的变构调节

期刊:Nature Structural & Molecular Biology

影响因子:10.1

doi:10.1038/s41594-020-0417-5

Llorente-Esteban, Alejandro; Manville, Rían W; Reyna-Neyra, Andrea; Abbott, Geoffrey W; Amzel, L Mario; Carrasco, Nancy

发表日期：2020

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Mentors: Ron Kaback

导师：罗恩·卡巴克

期刊:Journal of General Physiology

影响因子:2.9

doi:10.1085/jgp.201912322

Carrasco, Nancy

发表日期：2019

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Phenomic Impact of Genetically-Determined Euthyroid Function and Molecular Differences between Thyroid Disorders

遗传决定的甲状腺功能正常表型组学影响及甲状腺疾病的分子差异

期刊:Journal of Clinical Medicine

影响因子:2.9

doi:10.3390/jcm7100296

Ravera, Silvia; Carrasco, Nancy; Gelernter, Joel; Polimanti, Renato

免疫/内分泌

发表日期：2018

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The Sodium/Iodide Symporter (NIS): Molecular Physiology and Preclinical and Clinical Applications

钠/碘同向转运蛋白（NIS）：分子生理学、临床前和临床应用

期刊:Annual Review of Physiology

影响因子:19.1

doi:10.1146/annurev-physiol-022516-034125

Ravera, Silvia; Reyna-Neyra, Andrea; Ferrandino, Giuseppe; Amzel, L Mario; Carrasco, Nancy

发表日期：2017

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An extremely high dietary iodide supply forestalls severe hypothyroidism in Na(+)/I(-) symporter (NIS) knockout mice.

极高的膳食碘化物供应可预防 Na(+)/I(-) 同向转运蛋白 (NIS) 敲除小鼠出现严重的甲状腺功能减退症

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-017-04326-z

Ferrandino Giuseppe, Kaspari Rachel R, Reyna-Neyra Andrea, Boutagy Nabil E, Sinusas Albert J, Carrasco Nancy

免疫/内分泌

发表日期：2017

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