High glucose heightens vulnerability to Leishmania braziliensis infection in human macrophages by hampering the production of reactive oxygen species through TLR2 and TLR4
高血糖会通过抑制TLR2和TLR4介导的活性氧产生,从而增加人巨噬细胞对巴西利什曼原虫感染的易感性。
期刊:Emerging Microbes & Infections
影响因子:7.5
doi:10.1080/22221751.2025.2475824
Bonyek-Silva, Ícaro; Bastos, Rana; Nunes, Sara; Tibúrcio, Rafael; Lago, Alexsandro; Silva, Juliana; Carvalho, Lucas P; Khouri, Ricardo; Arruda, Sergio M; Barral, Aldina; Boaventura, Viviane; Serezani, Henrique C; Carvalho, Edgar M; Brodskyn, Cláudia Ida; Tavares, Natalia Machado
巨噬细胞
炎症/感染
巨噬细胞
TLR4
TLR2
细胞生物学
免疫/内分泌