日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Impact of Brain-Derived Neurotrophic Factor rs6265 (Val66Met) Polymorphism on Therapeutic Electrical Stimulation for Peripheral Nerve Regeneration: A Preclinical Study of Therapy-Genotype Interactions

脑源性神经营养因子rs6265(Val66Met)多态性对周围神经再生治疗性电刺激的影响:治疗-基因型相互作用的临床前研究

Jordan B Walters ,Maria J Quezada ,Suning He ,Ciara S Haynes ,Kathy Steece-Collier ,Timothy J Collier ,Caryl E Sortwell ,Colin K Franz

Alpha-synuclein inclusion responsive microglia are resistant to CSF1R inhibition

对 α-突触核蛋白包涵体有反应的小胶质细胞对 CSF1R 抑制有抵抗作用

Anna C Stoll, Christopher J Kemp, Joseph R Patterson, Michael Kubik, Nathan Kuhn, Matthew Benskey, Megan F Duffy, Kelvin C Luk, Caryl E Sortwell

Advancing age and the rs6265 BDNF SNP are permissive to graft-induced dyskinesias in parkinsonian rats

年龄增长和 rs6265 BDNF SNP 导致帕金森病大鼠发生移植物诱发的运动障碍

Natosha M Mercado #, Carlye Szarowicz #, Jennifer A Stancati, Caryl E Sortwell, Samuel A Boezwinkle, Timothy J Collier, Margaret E Caulfield, Kathy Steece-Collier

Transcriptomic profiling of early synucleinopathy in rats induced with preformed fibrils

用预先形成的纤维诱导的大鼠早期突触核蛋白病的转录组分析

Joseph R Patterson ,Joseph Kochmanski ,Anna C Stoll ,Michael Kubik ,Christopher J Kemp ,Megan F Duffy ,Kajene Thompson ,Jacob W Howe ,Allyson Cole-Strauss ,Nathan C Kuhn ,Kathryn M Miller ,Seth Nelson ,Christopher U Onyekpe ,John S Beck ,Scott E Counts ,Alison I Bernstein ,Kathy Steece-Collier ,Kelvin C Luk ,Caryl E Sortwell

Neuroinflammatory gene expression profiles of reactive glia in the substantia nigra suggest a multidimensional immune response to alpha synuclein inclusions

黑质反应性胶质细胞的神经炎症基因表达谱表明,针对α-突触核蛋白包涵体的免疫反应是多维度的。

Anna C Stoll ,Christopher J Kemp ,Joseph R Patterson ,Jacob W Howe ,Kathy Steece-Collier ,Kelvin C Luk ,Caryl E Sortwell ,Matthew J Benskey

Developmental exposure to the Parkinson's disease-associated organochlorine pesticide dieldrin alters dopamine neurotransmission in α-synuclein pre-formed fibril (PFF)-injected mice

发育过程中接触与帕金森病相关的有机氯农药狄氏剂会改变注射 α-突触核蛋白预形成纤维 (PFF) 的小鼠的多巴胺神经传递

Sierra L Boyd, Nathan C Kuhn, Joseph R Patterson, Anna C Stoll, Sydney A Zimmerman, Mason R Kolanowski, Joseph J Neubecker, Kelvin C Luk, Eric S Ramsson, Caryl E Sortwell, Alison I Bernstein

Microglial depletion does not impact alpha-synuclein aggregation or nigrostriatal degeneration in the rat preformed fibril model

小胶质细胞耗竭不会影响大鼠预形成纤维模型中的 α-突触核蛋白聚集或黑质纹状体变性

Anna C Stoll, Christopher J Kemp, Joseph R Patterson, Michael Kubik, Nathan Kuhn, Matthew Benskey, Megan F Duffy, Kelvin Luk, Caryl E Sortwell

Dopaminergic Positron Emission Tomography Imaging in the Alpha-Synuclein Preformed Fibril Model Reveals Similarities to Early Parkinson's Disease

α-突触核蛋白预形成纤维模型中的多巴胺能正电子发射断层扫描成像揭示了与早期帕金森病的相似性

Vesna Sossi, Joseph R Patterson, Siobhan McCormick, Christopher J Kemp, Kathryn M Miller, Anna C Stoll, Nathan Kuhn, Michael Kubik, Joseph Kochmanski, Kelvin C Luk, Caryl E Sortwell

α-Synuclein antisense oligonucleotides as a disease-modifying therapy for Parkinson's disease

α-突触核蛋白反义寡核苷酸作为帕金森病的疾病改良疗法

Tracy A Cole, Hien Zhao, Timothy J Collier, Ivette Sandoval, Caryl E Sortwell, Kathy Steece-Collier, Brian F Daley, Alix Booms, Jack Lipton, Mackenzie Welch, Melissa Berman, Luke Jandreski, Danielle Graham, Andreas Weihofen, Stephanie Celano, Emily Schulz, Allyson Cole-Strauss, Esteban Luna, Duc Qua

The BDNF Val66Met polymorphism (rs6265) enhances dopamine neuron graft efficacy and side-effect liability in rs6265 knock-in rats

BDNF Val66Met 多态性 (rs6265) 增强了 rs6265 敲入大鼠的多巴胺神经元移植功效和副作用倾向

Natosha M Mercado, Jennifer A Stancati, Caryl E Sortwell, Rebecca L Mueller, Samuel A Boezwinkle, Megan F Duffy, D Luke Fischer, Ivette M Sandoval, Fredric P Manfredsson, Timothy J Collier, Kathy Steece-Collier