1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia
1-(1-乙酰基哌啶-4-基)-3-金刚烷-1-基脲 (AR9281) 是一种强效、选择性强、口服有效的可溶性环氧化物水解酶抑制剂，在啮齿动物高血压和血糖异常模型中具有疗效。
期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2010.12.042
Anandan, Sampath-Kumar; Webb, Heather Kay; Chen, Dawn; Wang, Yi-Xin Jim; Aavula, Basker R; Cases, Sylvaine; Cheng, Ying; Do, Zung N; Mehra, Upasana; Tran, Vinh; Vincelette, Jon; Waszczuk, Joanna; White, Kathy; Wong, Kenneth R; Zhang, Le-Ning; Jones, Paul D; Hammock, Bruce D; Patel, Dinesh V; Whitcomb, Randall; MacIntyre, D Euan; Sabry, James; Gless, Richard
