日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Inhibition of FicD-mediated AMPylation and deAMPylation by isoprenoid diphosphates

异戊二烯二磷酸对FicD介导的AMP化和去AMP化的抑制作用

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2533457123
Blevins, Aubrie M; Peng, Wei; Kinch, Lisa N; Monshad, Zihan; Paredes, Andrea G; Volz, Christina; Rutter, Jared; Casey, Amanda K; Hicks, Kevin G; Orth, Kim
发表日期：2026
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Pre-clinical model of dysregulated FicD AMPylation causes diabetes by disrupting pancreatic endocrine homeostasis.

FicD AMPylation失调的临床前模型通过破坏胰腺内分泌稳态导致糖尿病

期刊:Molecular Metabolism
影响因子:6.6
doi:10.1016/j.molmet.2025.102120
Casey Amanda K, Stewart Nathan M, Zaidi Naqi, Gray Hillery F, Fields Hazel A, Sakurai Masahiro, Pinzon-Arteaga Carlos A, Evers Bret M, Wu Jun, Orth Kim
免疫/内分泌
糖尿病
发表日期：2025
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Inhibition of FicD-mediated AMPylation and deAMPylation by Isoprenoid Diphosphates

异戊二烯二磷酸对FicD介导的AMP化和去AMP化的抑制作用

期刊:
影响因子:
doi:10.64898/2025.12.08.693056
Blevins, Aubrie M; Peng, Wei; Kinch, Lisa N; Monshad, Zihan; Paredes, Andrea G; Volz, Christina; Rutter, Jared; Casey, Amanda K; Hicks, Kevin G; Orth, Kim
发表日期：2025
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FicD sensitizes cellular response to glucose fluctuations in mouse embryonic fibroblasts

FicD 可增强小鼠胚胎成纤维细胞对葡萄糖波动的细胞反应

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2400781121
Gulen, Burak; Blevins, Aubrie; Kinch, Lisa N; Servage, Kelly A; Stewart, Nathan M; Gray, Hillery F; Casey, Amanda K; Orth, Kim
成纤维细胞
细胞生物学
发表日期：2024
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FicD regulates adaptation to the unfolded protein response in the murine liver.

FicD 调节小鼠肝脏对未折叠蛋白反应的适应

期刊:Biochimie
影响因子:3
doi:10.1016/j.biochi.2024.05.012
Casey Amanda K, Stewart Nathan M, Zaidi Naqi, Gray Hillery F, Cox Amelia, Fields Hazel A, Orth Kim
其它
发表日期：2024
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FicD Sensitizes Cellular Response to Glucose Fluctuations in Mouse Embryonic Fibroblasts

FicD 增强小鼠胚胎成纤维细胞对葡萄糖波动的细胞反应

期刊:
影响因子:
doi:10.1101/2024.01.22.576705
Gulen, Burak; Kinch, Lisa N; Servage, Kelly A; Blevins, Aubrie; Stewart, Nathan M; Gray, Hillery F; Casey, Amanda K; Orth, Kim
成纤维细胞
细胞生物学
Mouse
发表日期：2024
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FicD regulates adaptation to the unfolded protein response in the murine liver

FicD 调节小鼠肝脏对未折叠蛋白反应的适应性

期刊:
影响因子:
doi:10.1101/2024.04.15.589620
Casey, Amanda K; Stewart, Nathan M; Zaidi, Naqi; Gray, Hillery F; Cox, Amelia; Fields, Hazel A; Orth, Kim
发表日期：2024
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Fic-mediated AMPylation tempers the unfolded protein response during physiological stress

Fic介导的AMP化作用可抑制生理应激期间的未折叠蛋白反应。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2208317119
Casey, Amanda K; Gray, Hillery F; Chimalapati, Suneeta; Hernandez, Genaro; Moehlman, Andrew T; Stewart, Nathan; Fields, Hazel A; Gulen, Burak; Servage, Kelly A; Stefanius, Karoliina; Blevins, Aubrie; Evers, Bret M; Krämer, Helmut; Orth, Kim
发表日期：2022
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Enzymes Involved in AMPylation and deAMPylation

参与AMP化和去AMP化的酶

期刊:Chemical Reviews
影响因子:55.8
doi:10.1021/acs.chemrev.7b00145
Casey, Amanda K; Orth, Kim
发表日期：2018
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Fic-mediated deAMPylation is not dependent on homodimerization and rescues toxic AMPylation in flies

Fic介导的去AMP化不依赖于同源二聚化，并且能够挽救果蝇体内的毒性AMP化。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M117.799296
Casey, Amanda K; Moehlman, Andrew T; Zhang, Junmei; Servage, Kelly A; Krämer, Helmut; Orth, Kim
毒理研究
发表日期：2017
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