日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

TDP-43 and other hnRNPs regulate cryptic exon inclusion of a key ALS/FTD risk gene, UNC13A

TDP-43 和其他 hnRNP 调节关键 ALS/FTD 风险基因 UNC13A 的隐秘外显子包含

Yuka Koike, Sarah Pickles, Virginia Estades Ayuso, Karen Jansen-West, Yue A Qi, Ziyi Li, Lillian M Daughrity, Mei Yue, Yong-Jie Zhang, Casey N Cook, Dennis W Dickson, Michael Ward, Leonard Petrucelli, Mercedes Prudencio

Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases

TMEM106B 在多种神经退行性疾病中的同型纤维化

Andrew Chang, Xinyu Xiang, Jing Wang, Carolyn Lee, Tamta Arakhamia, Marija Simjanoska, Chi Wang, Yari Carlomagno, Guoan Zhang, Shikhar Dhingra, Manon Thierry, Jolien Perneel, Bavo Heeman, Lauren M Forgrave, Michael DeTure, Mari L DeMarco, Casey N Cook, Rosa Rademakers, Dennis W Dickson, Leonard Petr

Evidence of cerebellar TDP-43 loss of function in FTLD-TDP

FTLD-TDP 中小脑 TDP-43 功能丧失的证据

Sarah Pickles #, Tania F Gendron #, Yuka Koike, Mei Yue, Yuping Song, Jennifer M Kachergus, J Shi, Michael DeTure, E Aubrey Thompson, Björn Oskarsson, Neill R Graff-Radford, Bradley F Boeve, Ronald C Petersen, Zbigniew K Wszolek, Keith A Josephs, Dennis W Dickson, Leonard Petrucelli, Casey N Cook, M

Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains

翻译后修饰介导 Tau 蛋白病菌株的结构多样性

Tamta Arakhamia, Christina E Lee, Yari Carlomagno, Duc M Duong, Sean R Kundinger, Kevin Wang, Dewight Williams, Michael DeTure, Dennis W Dickson, Casey N Cook, Nicholas T Seyfried, Leonard Petrucelli, Anthony W P Fitzpatrick

Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD

在 C9orf72 相关 FTD 中,毒性扩增的 GGGGCC 重复转录由 PAF1 复合物介导

Lindsey D Goodman, Mercedes Prudencio, Nicholas J Kramer, Luis F Martinez-Ramirez, Ananth R Srinivasan, Matthews Lan, Michael J Parisi, Yongqing Zhu, Jeannie Chew, Casey N Cook, Amit Berson, Aaron D Gitler, Leonard Petrucelli, Nancy M Bonini

The lysosomal protein cathepsin L is a progranulin protease

溶酶体蛋白组织蛋白酶 L 是一种前颗粒蛋白蛋白酶

Chris W Lee, Jeannette N Stankowski, Jeannie Chew, Casey N Cook, Ying-Wai Lam, Sandra Almeida, Yari Carlomagno, Kwok-Fai Lau, Mercedes Prudencio, Fen-Biao Gao, Matthew Bogyo, Dennis W Dickson, Leonard Petrucelli

Repetitive element transcripts are elevated in the brain of C9orf72 ALS/FTLD patients

C9orf72 ALS/FTLD 患者脑内重复元素转录本增多

Mercedes Prudencio, Patrick K Gonzales, Casey N Cook, Tania F Gendron, Lillian M Daughrity, Yuping Song, Mark T W Ebbert, Marka van Blitterswijk, Yong-Jie Zhang, Karen Jansen-West, Matthew C Baker, Michael DeTure, Rosa Rademakers, Kevin B Boylan, Dennis W Dickson, Leonard Petrucelli, Christopher D L