日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

GEF me a break: the consequences of freezing Rho guanine-nucleotide exchange factor catalytic domains

GEF 让我休息一下:Rho 鸟嘌呤核苷酸交换因子催化结构域冻结的后果

Anderson, Lauren K; Barpal, Emma; Mendoza, Herra; Cash, Jennifer N

P-Rex2 exhibits unique structural features and regulatory mechanisms distinct from the closely related RhoGEF P-Rex1

P-Rex2 具有独特的结构特征和调控机制,与密切相关的 RhoGEF P-Rex1 截然不同。

Anderson, Lauren K; Marde, Rohan; Muma, Grace; Nayak, Veda; Phan, Chi; Li, Sheng; Cash, Jennifer N

Structural/functional studies of Trio provide insights into its configuration and show that conserved linker elements enhance its activity for Rac1

Trio的结构/功能研究揭示了其构型,并表明保守的连接元件增强了其对Rac1的活性。

Bandekar, Sumit J; Chen, Chun-Liang; Ravala, Sandeep K; Cash, Jennifer N; Avramova, Larisa V; Zhalnina, Mariya V; Gutkind, J Silvio; Li, Sheng; Tesmer, John J G

Structural analyses of the PKA RIIβ holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma

对含有致癌性DnaJB1-PKAc融合蛋白的PKA RIIβ全酶的结构分析揭示了纤维板层肝细胞癌中原聚体不对称性和融合诱导的变构扰动。

Lu, Tsan-Wen; Aoto, Phillip C; Weng, Jui-Hung; Nielsen, Cole; Cash, Jennifer N; Hall, James; Zhang, Ping; Simon, Sanford M; Cianfrocco, Michael A; Taylor, Susan S

High-resolution cryo-EM using beam-image shift at 200 keV

利用200 keV的束像偏移技术进行高分辨率冷冻电镜成像

Cash, Jennifer N; Kearns, Sarah; Li, Yilai; Cianfrocco, Michael A

Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.

转移因子 P-Rex1 催化核心的结构和生化特征及其受 PtdIns(3,4,5)P3 调控

Cash Jennifer N, Davis Ellen M, Tesmer John J G