日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Reliable repurposing of the antibody interactome inside the cell

细胞内抗体相互作用组的可靠再利用

O'Shea, Caitlin M; Shahzad, Rushba; Aghasoleimani, Kimia; Newman, Stuart; Panmanee, Jiraporn; Schalkwyk, Leonard C; Brooke, Greg N; Benson, Fiona E; Trimmer, James S; Bosco, Daryl A; Fujisawa, Takao; Ichijo, Hidenori; Cashman, Neil R; Engel, Stanislav; Wright, Gareth S A

Longitudinal Analysis of Superoxide Dismutase 1 Seeding Activity in Amyotrophic Lateral Sclerosis Cerebrospinal Fluid

肌萎缩侧索硬化症脑脊液中超氧化物歧化酶1种子活性的纵向分析

Sebogo, Mylene A; Frans, Macie C; Paulose, Helan; Rodriguez, Claire L; Hsiung, Ging-Yuek; Cashman, Neil R; Ly, Cindy V; Leavens, Moses J

Development of a targeted BioPROTAC degrader selective for misfolded SOD1

开发一种针对错误折叠的SOD1的靶向BioPROTAC降解剂

Chisholm, Christen G; Bartlett, Rachael; Brown, Mikayla L; Proctor, Emma-Jayne; Farrawell, Natalie E; Gorman, Jody; Delerue, Fabien; Ittner, Lars M; Vine-Perrow, Kara L; Ecroyd, Heath; Cashman, Neil R; Saunders, Darren N; McAlary, Luke; Lum, Jeremy S; Yerbury, Justin J

Relationship between efficacy and preferential targeting of soluble Aβ aggregates

疗效与优先靶向可溶性Aβ聚集体之间的关系

Kaplan, Johanne M; Gibbs, Ebrima; Coutts, Juliane A; Zhao, Beibei; Mackenzie, Ian R; Plotkin, Steven S; Cashman, Neil R

Protein misfolding‐specific epitope identification for passive and active immunotherapy of neurodegenerative diseases

蛋白质错误折叠特异性表位鉴定用于神经退行性疾病的被动和主动免疫治疗

Tripathy, Swagata; Nair, Priya V; Cashman, Neil R; Plotkin, Steven S; Napper, Scott; Gibbs, Ebrima; Zhao, Beibei; Scruten, Erin; Coutts, Juliane; Kaplan, Johanne

Optimizing Epitope Conformational Ensembles Using α-Synuclein Cyclic Peptide "Glycindel" Scaffolds: A Customized Immunogen Method for Generating Oligomer-Selective Antibodies for Parkinson's Disease

利用α-突触核蛋白环肽“Glycindel”支架优化表位构象集合:一种用于生成帕金森病寡聚体选择性抗体的定制免疫原方法

Hsueh, Shawn C C; Aina, Adekunle; Roman, Andrei Yu; Cashman, Neil R; Peng, Xubiao; Plotkin, Steven S

A method for systematically ranking therapeutic drug candidates using multiple uncertain screening criteria

一种利用多个不确定筛选标准对候选治疗药物进行系统排序的方法

Peng, Xubiao; Gibbs, Ebrima; Silverman, Judith M; Cashman, Neil R; Plotkin, Steven S

Selenium-based compounds: Emerging players in the ever-unfolding story of SOD1 in amyotrophic lateral sclerosis

硒基化合物:肌萎缩侧索硬化症中SOD1作用机制不断演变的新兴参与者

Yerbury, Justin J; Cashman, Neil R

Passive immunotherapies targeting Aβ and tau in Alzheimer's disease

针对阿尔茨海默病中Aβ和tau蛋白的被动免疫疗法

Plotkin, Steven S; Cashman, Neil R

Amyotrophic Lateral Sclerosis: Proteins, Proteostasis, Prions, and Promises

肌萎缩侧索硬化症:蛋白质、蛋白质稳态、朊病毒和希望

McAlary, Luke; Chew, Yee Lian; Lum, Jeremy Stephen; Geraghty, Nicholas John; Yerbury, Justin John; Cashman, Neil R