日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Mutation type, tyrosine kinase function in normal cell and tyrosine kinase inhibitor activity in cancers

突变类型、酪氨酸激酶在正常细胞中的功能以及酪氨酸激酶抑制剂在癌症中的活性

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-026-41710-0
Vanacker, H; Cassier, P A; Dufresne, A; Pérol, M; Verlingue, Loic; Swalduz, A; Vinceneux, A; Attignon, V; Brahmi, M; Tredan, O; Tirode, F; Blay, J -Y
信号转导
细胞生物学
肿瘤
肿瘤免疫
发表日期：2026
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First-in-human phase 1 dose-escalation study of W0180, an anti-VISTA monoclonal antibody, with and without pembrolizumab in patients with locally advanced or metastatic solid tumours

首次人体1期剂量递增研究，评估抗VISTA单克隆抗体W0180联合或不联合帕博利珠单抗治疗局部晚期或转移性实体瘤患者的疗效。

期刊:
影响因子:
doi:10.1136/bmjonc-2025-000854
Gomez-Roca, Carlos; Champiat, Stéphane; Danlos, Francois-Xavier; Castañón Álvarez, Eduardo; Cassier, Philippe Alexandre; Dupuy, Elena; Jegou, David; Primard, Marie; Pétain, Aurélie; Saccareau, Mathilde; Gueguen-Dorbes, Geneviève; Fabre, Claire; Marabelle, Aurélien; Melero, Ignacio
单克隆抗体
VISTA
发表日期：2026
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Broad versus limited gene panels to guide treatment in patients with advanced solid tumors: a randomized controlled trial

广泛基因检测与有限基因检测在指导晚期实体瘤患者治疗中的应用：一项随机对照试验

期刊:Nature Medicine
影响因子:50
doi:10.1038/s41591-025-03613-x
Trédan, Olivier; Pouessel, Damien; Penel, Nicolas; Chabaud, Sylvie; Gomez-Roca, Carlos; Delord, Jean-Pierre; Pannier, Diane; Brahmi, Mehdi; Fabbro, Michel; Garcia, Marie-Eve; Larrieu-Ciron, Delphine; Ray-Coquard, Isabelle; Viala, Marie; Italiano, Antoine; Tosi, Diego; Cassier, Philippe; Dufresne, Armelle; Attignon, Valery; Boyault, Sandrine; Treilleux, Isabelle; Viari, Alain; Pérol, David; Blay, Jean Yves
发表日期：2025
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Divergence in a eukaryotic transcription factor's co-TF dependence involves multiple intrinsically disordered regions.

真核转录因子对共转录因子的依赖性差异涉及多个内在无序区域

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-59244-w
Snyder Lindsey F, O'Brien Emily M, Zhao Jia, Liang Jinye, Bruce Baylee J, Zhang Yuning, Zhu Wei, Cassier Thomas H, Schnicker Nicholas J, Zhou Xu, Gordân Raluca, He Bin Z
其它
发表日期：2025
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Nanrilkefusp alfa (SOT101), an IL-15 receptor βγ superagonist, as a single agent or with anti-PD-1 in patients with advanced cancers

Nanrilkefusp alfa (SOT101) 是一种 IL-15 受体 βγ 超激动剂，可作为单药或与抗 PD-1 药物联合用于治疗晚期癌症患者。

期刊:Cell Reports Medicine
影响因子:11.7
doi:10.1016/j.xcrm.2025.101967
Stephane Champiat ，Elena Garralda ，Vladimir Galvao ，Philippe A Cassier ，Carlos Gomez-Roca ，Iphigenie Korakis ，Peter Grell ，Aung Naing ，Patricia LoRusso ，Romana Mikyskova ，Nada Podzimkova ，Milan Reinis ，Kaissa Ouali ，Andreu Schoenenberger ，Joachim Kiemle-Kallee ，Sascha Tillmanns ，Richard Sachse ，Ulrich Moebius ，Radek Spisek ，David Bechard ，Lenka Palova Jelinkova ，Irena Adkins ，Aurelien Marabelle
PD-1
肿瘤
信号转导
肿瘤免疫
IL-15
发表日期：2025
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CD40 agonist mitazalimab with mFOLFIRINOX in untreated metastatic pancreatic cancer: Biomarkers associated with outcomes from OPTIMIZE-1

CD40激动剂mitazalimab联合mFOLFIRINOX方案治疗未经治疗的转移性胰腺癌：OPTIMIZE-1研究中与疗效相关的生物标志物

期刊:Cell Reports Medicine
影响因子:11.7
doi:10.1016/j.xcrm.2025.102407
Jean-Luc Van Laethem ，Karen Geboes ，Ivan Borbath ，Teresa Macarulla Mercade ，Aurélien Lambert ，Philippe Cassier ，Hans Prenen ，Emmanuel Mitry ，Jean-Frédéric Blanc ，Lorenzo Pilla ，Jaime Feliu ，Mercedes Rodriguez Garrote ，Roberto Antonio Pazo-Cid ，Inmaculada Gallego ，Karin Enell Smith ，Karin Nordbladh ，David Gomez Jimenez ，Peter Ellmark ，Yago Pico de Coaña ，Sumeet Vijay Ambarkhane ，Gregory L Beatty ，Eileen M O'Reilly
肿瘤
胰腺癌
T细胞
CD4
CD40
TAZ
发表日期：2025
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A Phase I Clinical Trial of Intrahepatic Artery Delivery of TG6002 in Combination with Oral 5-Fluorocytosine in Patients with Liver-Dominant Metastatic Colorectal Cancer.

一项 I 期临床试验，研究肝动脉内递送 TG6002 与口服 5-氟胞胞嘧啶联合治疗以肝脏转移为主的结直肠癌患者的疗效

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-24-2498
West Emma J, Sadoun Alain, Bendjama Kaidre, Erbs Philippe, Smolenschi Cristina, Cassier Philippe A, de Baere Thierry, Sainte-Croix Sophie, Brandely Maud, Melcher Alan A, Ismail Fay, Scott Karen J, Bennett Angela, Banks Emma, Gasior Ewa, Kent Sarah, Kurzawa Marta, Hammond Christopher, Patel Jai V, Collinson Fiona J, Twelves Chris, Anthoney D Alan, Swinson Dan, Samson Adel
肿瘤
肠癌
发表日期：2025
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Addressing screening failures in early-phase clinical trials in oncology: impact on patient outcomes and strategies for improvement

解决肿瘤早期临床试验中筛选失败的问题：对患者预后的影响及改进策略

期刊:ESMO Open
影响因子:8.3
doi:10.1016/j.esmoop.2025.105331
Korakis, I; Ouali, K; Hanvic, B; Verlingue, L; Allignet, B; Lusque, A; Clementei, S; Magne, E; Massard, C; Delord, J-P; Cassier, P; Baldini, C; Segier, B; Gomez-Roca, C
肿瘤
肿瘤免疫
发表日期：2025
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Lenvatinib plus pembrolizumab for patients with previously treated select solid tumors: Results from the phase 2 LEAP-005 study recurrent glioblastoma cohort

乐伐替尼联合帕博利珠单抗治疗既往接受过治疗的特定实体瘤患者：来自 LEAP-005 II 期研究复发性胶质母细胞瘤队列的结果

期刊:Cancer
影响因子:5.1
doi:10.1002/cncr.70015
Rha, Sun Young; Castanon, Eduardo; Gill, Sanjeev; Senellart, Helene; Lopez, Juanita; Márquez-Rodas, Iván; Victoria, Iván; Kim, Tae Min; Lwin, Zarnie; Burger, Michael C; Simonelli, Matteo; Cassier, Philippe A; Hendifar, Andrew E; Ascierto, Paolo A; Dutcus, Corina; Okpara, Chinyere E; Ghori, Razi; Jin, Fan; Groisberg, Roman; Villanueva, Luis
细胞生物学
发表日期：2025
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Understanding Serratia bockelmannii transmission during a neonatal intensive care unit outbreak: a combined genotyping and case-control study

了解新生儿重症监护病房暴发期间博克尔曼氏沙雷氏菌的传播：一项结合基因分型和病例对照的研究

期刊:Antimicrobial Resistance and Infection Control
影响因子:4.4
doi:10.1186/s13756-025-01632-4
Jaakkola, Kaisa; Fischer, Aurélie; Piquart, Louise; Cassier, Pierre; Dauwalder, Olivier; Picaud, Jean-Charles; Colomb-Cotinat, Mélanie; Haÿs, Stéphane; Rasigade, Jean-Philippe; Dananché, Cédric
发表日期：2025
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