日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

High resistance barrier and prophylactic protection in preclinical models of SARS-CoV-2 with two siRNA combination.

两种 siRNA 组合在 SARS-CoV-2 临床前模型中表现出高抵抗屏障和预防性保护作用

Anglero-Rodriguez Yesseinia I, Lempp Florian A, Subramanian Megha, McIninch James, Schlegel Mark K, Bohan Dana, Wong Emily, Brown Christopher R, Foster Donald J, Castoreno Adam B, Nguyen Tuyen, Cuffe Dara, Montiel-Ruiz Martin, Kaiser Hannah, Sahakyan Anna, Spreafico Roberto, Morskaya Svetlana Shulga, Barry Joseph D, Berman Daniel, Zhang Ligang, Lefebvre Stephanie, Kasper Anne, Racie Timothy, Weddle Diann, Mobley Melissa, Wassarman Kelly, Bisbe Anna, Zlatev Ivan, Rogers Arlin, Nechev Lubomir, Dybowski Joseph, Chong Saeho, Nair Jayaprakash, Simon Amy, Sloan Kevin, Hwang Seungmin, Virgin Herbert W, Fitzgerald Kevin, Maier Martin A, Hinkle Gregory, Hebner Christy M, Akinc Akin, Jadhav Vasant

Discovery of a Small-Molecule Probe for V-ATPase Function

发现一种用于检测V-ATPase功能的小分子探针

Aldrich, Leslie N; Kuo, Szu-Yu; Castoreno, Adam B; Goel, Gautam; Kuballa, Petric; Rees, Matthew G; Seashore-Ludlow, Brinton A; Cheah, Jaime H; Latorre, Isabel J; Schreiber, Stuart L; Shamji, Alykhan F; Xavier, Ramnik J

Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics

小分子自噬增强剂可调节细胞疾病表型,这已通过人类遗传学得到证实。

Kuo, Szu-Yu; Castoreno, Adam B; Aldrich, Leslie N; Lassen, Kara G; Goel, Gautam; Dančík, Vlado; Kuballa, Petric; Latorre, Isabel; Conway, Kara L; Sarkar, Sovan; Maetzel, Dorothea; Jaenisch, Rudolf; Clemons, Paul A; Schreiber, Stuart L; Shamji, Alykhan F; Xavier, Ramnik J

Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection

Atg16l1是肠道上皮细胞自噬所必需的,并且能够保护小鼠免受沙门氏菌感染。

Conway, Kara L; Kuballa, Petric; Song, Joo-Hye; Patel, Khushbu K; Castoreno, Adam B; Yilmaz, Omer H; Jijon, Humberto B; Zhang, Mei; Aldrich, Leslie N; Villablanca, Eduardo J; Peloquin, Joanna M; Goel, Gautam; Lee, In-Ah; Mizoguchi, Emiko; Shi, Hai Ning; Bhan, Atul K; Shaw, Stanley Y; Schreiber, Stuart L; Virgin, Herbert W; Shamji, Alykhan F; Stappenbeck, Thaddeus S; Reinecker, Hans-Christian; Xavier, Ramnik J

Inflammatory Bowel Disease at the Intersection of Autophagy and Immunity: Insights from Human Genetics

炎症性肠病:自噬与免疫的交汇点——来自人类遗传学的启示

Tang, Guomei; Gudsnuk, Kathryn; Kuo, Sheng-Han; Cotrina, Marisa L; Rosoklija, Gorazd; Sosunov, Alexander; Sonders, Mark S; Kanter, Ellen; Castagna, Candace; Yamamoto, Ai; Yue, Zhenyu; Arancio, Ottavio; Peterson, Bradley S; Champagne, Frances; Dwork, Andrew J; Goldman, James; Sulzer, David; Nedelsky, Natalia; Kuballa, Petric; Castoreno, Adam B; Xavier, Ramnik J; Nedelsky, Natalia B; Kuballa, Petric; Castoreno, Adam B; Xavier, Ramnik J

Selective modulation of autophagy, innate immunity, and adaptive immunity by small molecules

小分子对自噬、固有免疫和适应性免疫的选择性调节

Shaw, Stanley Y; Tran, Khoa; Castoreno, Adam B; Peloquin, Joanna M; Lassen, Kara G; Khor, Bernard; Aldrich, Leslie N; Tan, Pauline H; Graham, Daniel B; Kuballa, Petric; Goel, Gautam; Daly, Mark J; Shamji, Alykhan F; Schreiber, Stuart L; Xavier, Ramnik J

Inflammatory Bowel Disease at the Intersection of Autophagy and Immunity: Insights from Human Genetics

炎症性肠病:自噬与免疫的交汇点——来自人类遗传学的启示

Perez-Rodriguez, M Mercedes; New, Antonia S; Goldstein, Kim E; Rosell, Daniel; Yuan, Qiaoping; Zhou, Zhifeng; Hodgkinson, Colin; Goldman, David; Siever, Larry J; Hazlett, Erin A; Nedelsky, Natalia; Kuballa, Petric; Castoreno, Adam B; Xavier, Ramnik J; Nedelsky, Natalia B; Kuballa, Petric; Castoreno, Adam B; Xavier, Ramnik J

Small molecule probes of cellular pathways and networks

细胞通路和网络的小分子探针

Castoreno, Adam B; Eggert, Ulrike S

Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis.

在通路筛选中发现的小分子靶向胞质分裂中的 Rho 通路

Castoreno Adam B, Smurnyy Yegor, Torres Angelica D, Vokes Martha S, Jones Thouis R, Carpenter Anne E, Eggert Ulrike S

Making the cut: the chemical biology of cytokinesis.

细胞分裂的化学生物学

Atilla-Gokcumen G Ekin, Castoreno Adam B, Sasse Sofia, Eggert Ulrike S