The dopamine analogue CA140 alleviates AD pathology, neuroinflammation, and rescues synaptic/cognitive functions by modulating DRD1 signaling or directly binding to Abeta
多巴胺类似物 CA140 通过调节 DRD1 信号或直接结合 Abeta 来缓解 AD 病理、神经炎症并挽救突触/认知功能
期刊:Journal of Neuroinflammation
影响因子:9.3
doi:10.1186/s12974-024-03180-x
Sehyun Chae #, Hyun-Ju Lee #, Ha-Eun Lee #, Jieun Kim, Yoo Joo Jeong, Yuxi Lin, Hye Yun Kim, Geoffray Leriche, Rachel S Ehrlich, Sascha Castro Lingl, Min-Duk Seo, Young-Ho Lee, Jerry Yang, Jae-Ick Kim, Hyang-Sook Hoe
信号转导
免疫
神经
神经炎症
Immunology/Inflammation
Neuroscience
