日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The PD-L1- and IL6-mediated dampening of the IL27/STAT1 anticancer responses are prevented by α-PD-L1 or α-IL6 antibodies

α-PD-L1 或 α-IL6 抗体可阻止 PD-L1 和 IL6 介导的 IL27/STAT1 抗癌反应抑制

Catherine Rolvering, Andreas D Zimmer, Aurélien Ginolhac, Christiane Margue, Mélanie Kirchmeyer, Florence Servais, Heike M Hermanns, Sabine Hergovits, Petr V Nazarov, Nathalie Nicot, Stephanie Kreis, Serge Haan, Iris Behrmann, Claude Haan

Crosstalk between different family members: IL27 recapitulates IFNγ responses in HCC cells, but is inhibited by IL6-type cytokines

不同家族成员之间的串扰:IL27 重现 HCC 细胞中的 IFNγ 反应,但受到 IL6 型细胞因子的抑制

Catherine Rolvering, Andreas D Zimmer, Ines Kozar, Heike M Hermanns, Elisabeth Letellier, Laurent Vallar, Petr V Nazarov, Nathalie Nicot, Aurélien Ginolhac, Serge Haan, Iris Behrmann, Claude Haan

The oncogenic FIP1L1-PDGFRα fusion protein displays skewed signaling properties compared to its wild-type PDGFRα counterpart

致癌 FIP1L1-PDGFRα 融合蛋白与野生型 PDGFRα 对应物相比,表现出偏差的信号传导特性

Serge Haan, Christelle Bahlawane, Jiali Wang, Petr V Nazarov, Arnaud Muller, René Eulenfeld, Claude Haan, Catherine Rolvering, Laurent Vallar, Venkata P Satagopam, Thomas Sauter, Monique Yvonne Wiesinger

Cooperative effects of Janus and Aurora kinase inhibition by CEP701 in cells expressing Jak2V617F

CEP701 对表达 Jak2V617F 的细胞中 Janus 和 Aurora 激酶的抑制的协同作用

Karoline Gäbler, Catherine Rolvering, Jakub Kaczor, René Eulenfeld, Sergio Álvarez Méndez, Guy Berchem, Valérie Palissot, Iris Behrmann, Claude Haan

JAK2-V617F-induced MAPK activity is regulated by PI3K and acts synergistically with PI3K on the proliferation of JAK2-V617F-positive cells

JAK2-V617F 诱导的 MAPK 活性受 PI3K 调控,并与 PI3K 协同作用,促进 JAK2-V617F 阳性细胞的增殖

Alexandra Wolf, René Eulenfeld, Karoline Gäbler, Catherine Rolvering, Serge Haan, Iris Behrmann, Bernd Denecke, Claude Haan, Fred Schaper