Lactate signalling leads to aggregation of immune-inflammatory hotspots and SLC5A12 blockade promotes their resolution.
乳酸信号传导导致免疫炎症热点聚集,而 SLC5A12 阻断可促进其消退
期刊:Nature Metabolism
影响因子:20.8
doi:10.1038/s42255-025-01331-9
Certo Michelangelo, Pontarini Elena, Gilbert Sebastian G, Schmidt Ronny, Turner Jason D, Lucchesi Davide, Apostolo Daria, Cavallaro Giulia, Smith Charlotte G, Colafrancesco Serena, Campos Joana, Nayar Saba, Schröder Christoph, Fisher Benjamin A, Spill Fabian, Bombardieri Michele, Mauro Claudio