日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticity.

HMGA2 和蛋白质亮氨酸甲基化驱动胰腺癌谱系可塑性

Dobersch Stephanie, Yamamoto Naomi, Schutter Aidan, Cavender Sarah M, Robertson Tess M, Kartha Nithya, Samraj Annie N, Doron Ben, Poole Lisa A, Wladyka Cynthia L, Zhang Amy, Jang Gun Ho, Mahalingam Aswanth H, Barreto Guillermo, Raghavan Srivatsan, Narla Goutham, Notta Faiyaz, Eisenman Robert N, Hsieh Andrew C, Kugel Sita

The PRL2 phosphatase up-regulates miR-21 through activation of the JAK2/STAT3 pathway to down-regulate the PTEN tumor suppressor.

PRL2 磷酸酶通过激活 JAK2/STAT3 通路上调 miR-21,从而下调 PTEN 肿瘤抑制因子

Li Qinglin, Bai Yunpeng, Cavender Sarah M, Miao Yiming, Nguele Meke Frederick, Lasse-Opsahl Emily L, Zhu Peipei, Doody Gina M, Tao W Andy, Zhang Zhong-Yin