日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis

EGFR 对 DCBLD2 的磷酸化募集 TRAF6 并刺激 AKT 促进的肿瘤发生

Feng, Haizhong; Lopez, Giselle Y; Kim, Chung Kwon; Alvarez, Angel; Duncan, Christopher G; Nishikawa, Ryo; Nagane, Motoo; Su, An-Jey A; Auron, Philip E; Hedberg, Matthew L; Wang, Lin; Raizer, Jeffery J; Kessler, John A; Parsa, Andrew T; Gao, Wei-Qiang; Kim, Sung-Hak; Minata, Mutsuko; Nakano, Ichiro; Grandis, Jennifer R; McLendon, Roger E; Bigner, Darell D; Lin, Hui-Kuan; Furnari, Frank B; Cavenee, Webster K; Hu, Bo; Yan, Hai; Cheng, Shi-Yuan

Retraction of Activation of Rac1 by Src-dependent phosphorylation of Dock180Y1811 mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans

Src依赖性Dock180Y1811磷酸化抑制Rac1的激活,从而介导PDGFRα刺激的小鼠和人类胶质瘤发生。

Feng, Haizhong; Hu, Bo; Liu, Kun-Wei; Li, Yanxin; Lu, Xinghua; Cheng, Tao; Yiin, Jia-Jean; Lu, Songjian; Keezer, Susan; Fenton, Tim; Furnari, Frank B; Hamilton, Ronald L; Vuori, Kristiina; Sarkaria, Jann N; Nagane, Motoo; Nishikawa, Ryo; Cavenee, Webster K; Cheng, Shi-Yuan

A zinc transporter drives glioblastoma progression via extracellular vesicles-reprogrammed microglial plasticity

锌转运蛋白通过细胞外囊泡重编程小胶质细胞可塑性驱动胶质母细胞瘤进展

Zhang, Liyang; Yang, Jingxuan; Zhou, Zhijun; Ren, Yu; Chen, Bo; Tang, Anliu; Zhang, Kailiang; Li, Chuntao; Zhou, Hongshu; Fung, Kar-Ming; Xu, Chao; Kang, Chunsheng; Battiste, James D; Bronze, Michael S; Houchen, Courtney W; Liu, Zhixiong; Dunn, Ian F; Cavenee, Webster K; Li, Min

Somatic 9p24.1 alterations in HPV(-) head and neck squamous cancer dictate immune microenvironment and anti-PD-1 checkpoint inhibitor activity

HPV阴性头颈部鳞状细胞癌中9p24.1的体细胞改变决定免疫微环境和抗PD-1检查点抑制剂的活性。

Zhao, Xin; Cohen, Ezra E W; William, William N Jr; Bianchi, Joy J; Abraham, Jim P; Magee, Daniel; Spetzler, David B; Gutkind, J Silvio; Alexandrov, Ludmil B; Cavenee, Webster K; Lippman, Scott M; Davoli, Teresa

The metabolomic landscape plays a critical role in glioma oncogenesis

代谢组学图谱在胶质瘤的发生发展中起着至关重要的作用。

Masui, Kenta; Cavenee, Webster K; Mischel, Paul S; Shibata, Noriyuki

Insights into the Mechanisms of Action of MDA-7/IL-24: A Ubiquitous Cancer-Suppressing Protein

深入了解MDA-7/IL-24的作用机制:一种普遍存在的抑癌蛋白

Modi, Jinkal; Roy, Abhishek; Pradhan, Anjan K; Kumar, Amit; Talukdar, Sarmistha; Bhoopathi, Praveen; Maji, Santanu; Mannangatti, Padmanabhan; Sanchez De La Rosa, Daniel; Li, Jiong; Guo, Chunqing; Subler, Mark A; Windle, Jolene J; Cavenee, Webster K; Sarkar, Devanand; Wang, Xiang-Yang; Das, Swadesh K; Emdad, Luni; Fisher, Paul B

Protein Acetylation at the Interface of Genetics, Epigenetics and Environment in Cancer

癌症中遗传、表观遗传和环境相互作用下的蛋白质乙酰化

Harachi, Mio; Masui, Kenta; Cavenee, Webster K; Mischel, Paul S; Shibata, Noriyuki

Lumefantrine, an antimalarial drug, reverses radiation and temozolomide resistance in glioblastoma

抗疟疾药物卢美芬汀可逆转胶质母细胞瘤的放射线和替莫唑胺耐药性

Rajesh, Yetirajam; Biswas, Angana; Kumar, Utkarsh; Banerjee, Indranil; Das, Subhayan; Maji, Santanu; Das, Swadesh K; Emdad, Luni; Cavenee, Webster K; Mandal, Mahitosh; Fisher, Paul B

Blockade of a Laminin-411-Notch Axis with CRISPR/Cas9 or a Nanobioconjugate Inhibits Glioblastoma Growth through Tumor-Microenvironment Cross-talk

利用 CRISPR/Cas9 或纳米生物缀合物阻断层粘连蛋白-411-Notch 轴可通过肿瘤微环境相互作用抑制胶质母细胞瘤生长

Sun, Tao; Patil, Rameshwar; Galstyan, Anna; Klymyshyn, Dmytro; Ding, Hui; Chesnokova, Alexandra; Cavenee, Webster K; Furnari, Frank B; Ljubimov, Vladimir A; Shatalova, Ekaterina S; Wagner, Shawn; Li, Debiao; Mamelak, Adam N; Bannykh, Serguei I; Patil, Chirag G; Rudnick, Jeremy D; Hu, Jethro; Grodzinski, Zachary B; Rekechenetskiy, Arthur; Falahatian, Vida; Lyubimov, Alexander V; Chen, Yongmei L; Leoh, Lai S; Daniels-Wells, Tracy R; Penichet, Manuel L; Holler, Eggehard; Ljubimov, Alexander V; Black, Keith L; Ljubimova, Julia Y

The RB1 Story: Characterization and Cloning of the First Tumor Suppressor Gene

RB1的故事:第一个抑癌基因的特性鉴定和克隆

Berry, Jesse L; Polski, Ashley; Cavenee, Webster K; Dryja, Thaddeus P; Murphree, A Linn; Gallie, Brenda L