SETD2 suppresses tumorigenesis in a KRAS(G12C)-driven lung cancer model and its catalytic activity is regulated by histone acetylation.
SETD2 在 KRAS(G12C) 驱动的肺癌模型中抑制肿瘤发生，其催化活性受组蛋白乙酰化的调控
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doi:10.1101/2025.05.16.654513
Mack Ricardo J, Flores Natasha M, Fox Geoffrey C, Dong Hanyang, Cebeci Metehan, Hausmann Simone, Chasan Tourkian, Dowen Jill M, Strahl Brian D, Mazur Pawel K, Gozani Or
