日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lupus Susceptibility Region Containing CDKN1B rs34330 Mechanistically Influences Expression and Function of Multiple Target Genes, Also Linked to Proliferation and Apoptosis

含有 CDKN1B rs34330 的狼疮易感区域以机制方式影响多个靶基因的表达和功能,还与增殖和细胞凋亡相关

Bhupinder Singh, Guru P Maiti, Xujie Zhou, Mehdi Fazel-Najafabadi, Sang-Cheol Bae, Celi Sun, Chikashi Terao, Yukinori Okada, Kek Heng Chua, Yuta Kochi, Joel M Guthridge, Hong Zhang, Matthew Weirauch, Judith A James, John B Harley, Gaurav K Varshney, Loren L Looger, Swapan K Nath

Mechanistic Characterization of RASGRP1 Variants Identifies an hnRNP-K-Regulated Transcriptional Enhancer Contributing to SLE Susceptibility

RASGRP1 变体的机制表征确定了导致 SLE 易感性的 hnRNP-K 调节转录增强子

Julio E Molineros, Bhupinder Singh, Chikashi Terao, Yukinori Okada, Jakub Kaplan, Barbara McDaniel, Shuji Akizuki, Celi Sun, Carol F Webb, Loren L Looger, Swapan K Nath

A Rare Variant (rs933717) at FBXO31-MAP1LC3B in Chinese Is Associated With Systemic Lupus Erythematosus

FBXO31-MAP1LC3B 的罕见变异 (rs933717) 与中国人系统性红斑狼疮有关

Yuan-Yuan Qi, Xu-Jie Zhou, Swapan K Nath, Celi Sun, Yan-Na Wang, Ping Hou, Rong Mu, Chun Li, Jian-Ping Guo, Zhan-Guo Li, Geng Wang, Hu-Ji Xu, Yan-Jie Hao, Zhuo-Li Zhang, Wei-Hua Yue, Huoru Zhang, Ming-Hui Zhao, Hong Zhang

Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription

两种功能性狼疮相关 BLK 启动子变体控制细胞类型和发育阶段特异性转录

Joel M Guthridge, Rufei Lu, Harry Sun, Celi Sun, Graham B Wiley, Nicolas Dominguez, Susan R Macwana, Christopher J Lessard, Xana Kim-Howard, Beth L Cobb, Kenneth M Kaufman, Jennifer A Kelly, Carl D Langefeld, Adam J Adler, Isaac T W Harley, Joan T Merrill, Gary S Gilkeson, Diane L Kamen, Timothy B N

Combined protein- and nucleic acid-level effects of rs1143679 (R77H), a lupus-predisposing variant within ITGAM

rs1143679 (R77H)(ITGAM 中的一种狼疮易感变异)的蛋白质和核酸水平的综合效应

Amit K Maiti, Xana Kim-Howard, Prasenjeet Motghare, Vandana Pradhan, Kek Heng Chua, Celi Sun, María Teresa Arango-Guerrero, Kanjaksha Ghosh, Timothy B Niewold, John B Harley, Juan-Manual Anaya, Loren L Looger, Swapan K Nath

Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production

狼疮中的混合映射识别出 IFIH1 内与细胞凋亡、炎症和自身抗体产生相关的多种功能变异

Julio E Molineros, Amit K Maiti, Celi Sun, Loren L Looger, Shizhong Han, Xana Kim-Howard, Stuart Glenn, Adam Adler, Jennifer A Kelly, Timothy B Niewold, Gary S Gilkeson, Elizabeth E Brown, Graciela S Alarcón, Jeffrey C Edberg, Michelle Petri, Rosalind Ramsey-Goldman, John D Reveille, Luis M Vilá, Ba