Human Induced Pluripotent Stem Cell-Derived Microglia-Like Cells Harboring TREM2 Missense Mutations Show Specific Deficits in Phagocytosis
携带 TREM2 错义突变的人类诱导性多能干细胞衍生的小胶质细胞样细胞表现出吞噬作用的特定缺陷
期刊:Cell Reports
影响因子:7.5
doi:10.1016/j.celrep.2018.07.094
Pablo Garcia-Reitboeck, Alexandra Phillips, Thomas M Piers, Claudio Villegas-Llerena, Matt Butler, Anna Mallach, Celia Rodrigues, Charles E Arber, Amanda Heslegrave, Henrik Zetterberg, Harald Neumann, Stephen Neame, Henry Houlden, John Hardy, Jennifer M Pocock
