DSP107 combines inhibition of CD47/SIRPα axis with activation of 4-1BB to trigger anticancer immunity
DSP107 结合了 CD47/SIRPα 轴的抑制和 4-1BB 的激活，从而触发抗肿瘤免疫。
期刊:Journal of Experimental & Clinical Cancer Research
影响因子:12.8
doi:10.1186/s13046-022-02256-x
Cendrowicz, Ewa; Jacob, Lisa; Greenwald, Shirley; Tamir, Ami; Pecker, Iris; Tabakman, Rinat; Ghantous, Lucy; Tamir, Liat; Kahn, Roy; Avichzer, Jasmine; Aronin, Alexandra; Amsili, Shira; Zorde-Khvalevsky, Elina; Gozlan, Yosi; Vlaming, Martijn; Huls, Gerwin; van Meerten, Tom; Dranitzki, Michal Elhalel; Foley-Comer, Adam; Pereg, Yaron; Peled, Amnon; Chajut, Ayelet; Bremer, Edwin
肿瘤
T细胞
肿瘤免疫
CD47
SP1
CD4
免疫/内分泌
