日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Benzoxaboroles Are Inhibitors of the η-Class Carbonic Anhydrase From Plasmodium falciparum

苯并硼氧杂环己烷是恶性疟原虫η类碳酸酐酶的抑制剂

Bonardi, Alessandro; Wein, Sharon; Mustafa, Muhamad; Cerdan, Rachel; de Luca, Viviana; Capasso, Clemente; Gratteri, Paola; Supuran, Claudiu T; Nocentini, Alessio; Winum, Jean-Yves

An acyclic nucleoside phosphonate effectively blocks the egress of the malaria parasite by inhibiting the synthesis of cyclic GMP

一种非环状核苷膦酸酯通过抑制环磷酸鸟苷(cGMP)的合成,有效阻断疟原虫的逸出。

Ali, Marie; Dura, Rea; Guery, Marc-Antoine; Colard-Itté, Emma; Cheviet, Thomas; Robresco, Léa; Berry, Laurence; Lionne, Corinne; Lavazec, Catherine; Claessens, Antoine; Peyrottes, Suzanne; Wengelnik, Kai; Wein, Sharon; Cerdan, Rachel

PI3-kinase has multiple functions in asexual blood stages of Plasmodium falciparum.

PI3激酶在恶性疟原虫的无性血液阶段具有多种功能

Al Monla Reem, Penzo Maria, Vallentin Alice, Lohia Rakhee, Vincent Jeremy, Berry Laurence, Gomes Ana Rita, Cerdan Rachel, Wengelnik Kai

A Single Interfacial Point Mutation Rescues Solution Structure Determination of the Complex of HMG-D with a DNA Bulge

单个界面点突变挽救了HMG-D与DNA凸起复合物的溶液结构测定

Hill, Guy R; Yang, Ji-Chun; Easton, Laura E; Cerdan, Rachel; McLaughlin, Stephen H; Stott, Katherine; Travers, Andrew A; Neuhaus, David

High Accumulation and In Vivo Recycling of the New Antimalarial Albitiazolium Lead to Rapid Parasite Death

新型抗疟药阿比特唑的高蓄积性和体内循环利用导致寄生虫迅速死亡

Wein, Sharon; Taudon, Nicolas; Maynadier, Marjorie; Tran Van Ba, Christophe; Margout, Delphine; Bordat, Yann; Fraisse, Laurent; Wengelnik, Kai; Cerdan, Rachel; Bressolle-Gomeni, Françoise; Vial, Henri J

Reliability of antimalarial sensitivity tests depends on drug mechanisms of action

抗疟药敏感性试验的可靠性取决于药物的作用机制。

Wein, Sharon; Maynadier, Marjorie; Tran Van Ba, Christophe; Cerdan, Rachel; Peyrottes, Suzanne; Fraisse, Laurent; Vial, Henri

Characterization of the lipid-binding domain of the Plasmodium falciparum CTP:phosphocholine cytidylyltransferase through synthetic-peptide studies

通过合成肽研究对恶性疟原虫CTP:磷酸胆碱胞苷酰转移酶的脂质结合域进行表征

Larvor, Marie-Pierre; Cerdan, Rachel; Gumila, Catherine; Maurin, Luc; Seta, Patrick; Roustan, Claude; Vial, Henri